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Home/Pharma information/How long does Pregabalin take to work

How long does Pregabalin take to work

Posted by : admin / On : June 2, 2021 / In : Pharma information
How long does Pregabalin take to work?

Table of Contents

  • How long does Pregabalin take to work?
    • Pregabalin treating different conditions:
    • The righter way of use, the better it works:
    • How long does Pregabalin take to work?
    • The relation between Pregabalin Rapid Absorption and how long does Pregabalin take to work:
    • How long does Pregabalin stay in your body?
    • Factors affecting how long it stays in your body:
    • How long does Pregabalin stay in Blood, Urine, and Hair?
    • Too Much Pregabalin:
    • Clinical Monitoring:

How long does Pregabalin take to work?

Before we talk about the time interval required for the Patient to feel better by using Pregabalin, how long does Pregabalin take to work, and to what extent Pregabalin is the drug of the choice, it’s important to know that the effect of Pregabalin differs from one patient to another, from case to another, and from dose to dose?

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Pregabalin treating different conditions:

  • In fact, the way Pregabalin work for pain management, for example, is that it blocks the effect of damaged nerves responsible for sending false messages to the brain causing pain. Pregabalin changes the way these nerves work or it may calm overactive nerves which means it is a good helper with other analgesics to reduce pain by a different mechanism and shorter time to feel better.
  • In patients with neuropathic pain (diabetic neuropathy or postherpetic neuralgia) time to onset of pregabalin analgesic effect under fixed-dose recorded a marked rapid onset of action.
  • When you hear about the patients’ (suffering from anxiety disorders) reviews about this medicine, you find out that about 83 % of them were satisfied by its positive rapid action helping them cool down quickly. That is due to its capability to prevent the release of chemicals in the brain that makes you feel anxious.

The righter way of use, the better it works:

To get the best benefit and the fastest progress leading to a shorter time for Pregabalin to work, use Pregabalin in the right way:

  • It is recommended to take Pregabalin exactly as the doctor prescribed without changing any of the instructions he said.
  • Take Pregabalin at the same time every day.
  • Take Pregabalin with or without food but it is preferred to take the evening dose after a good meal.
  • Avoid missing pregabalin dose (if so take it once you remember that, however, avoid taking two doses at the same time).
  • Avoid stopping it suddenly as it may lead to worsening the condition.
  • Of course, do not stop it without talking to your medical health provider.

Back to the main question:

How long does Pregabalin take to work?

After following the previous instructions and using Pregabalin in the right way, considering the different conditions and doses for different patients:

  • Some patients may experience pain decrease in the first week of treatment or even in the first few days.
  • Other patients may start to feel better in the second week.
  • For others, it may take a longer time according to the severity of the case, the dose of Pregabalin, and other factors. if so, you may ask your doctor for help by adjusting the dose or give you other recommendations according to the condition.

Pregabalin could be taken for a long period if it helps, you may need to gradually decrease the dose after a while to check if the pain still exists or you became much better now, but don’t stop it suddenly, you should refer to your doctor first.

 

How long does Pregabalin take to work

The relation between Pregabalin Rapid Absorption and how long does Pregabalin take to work:

Pregabalin is rapidly absorbed after oral administration. In comparison to Gabapentin’s bioavailability (from 30 – 60%), the oral bioavailability of Pregabalin is over 90% whatever the dose received. Both Gabapentinoids (Pregabalin & Gabapentin) are absorbed across the gastrointestinal tract. The rate of Pregabalin absorption is threefold higher than that of Gabapentin, that’s why Pregabalin achieves faster peak blood concentration compared with Gabapentin

 

How long does Pregabalin stay in your body?

Depending on various personal factors, it stays about 33 hours higher or lower according to the patient’s age, food, and other medications.

Factors affecting how long it stays in your body:

  • Age
  • Dosage
  • Kidney function
  • Hydration
  • Body mass
  • PH of urine
  • Duration of taking the medication

Pregabalin oral clearance is likely to decrease with increasing age, therefore, for older patients dose reduction should be considered.

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How long does Pregabalin stay in Blood, Urine, and Hair?

  • In blood, it stays about 2 days after your last dose.
  • In urine, it stays a litter bit longer than in blood (few days depending on the dosage).
  • In hair, it stays much longer than in blood and urine, may be up to 3 months.

Too Much Pregabalin:

If you think you have taken too much of Pregabalin or you experience one or more of the following symptoms, call your health care provider at once:

  • Drowsiness
  • Dizziness
  • Headache
  • Nervousness
  • Lack of control of the body movements
  • Tremors
  • Amnesia

Clinical Monitoring:

– To make sure that you stay safe while taking Pregabalin your doctor may ask you to do certain blood tests to check if you need to take a lower dose according to how well your kidneys are working.

– Changes in mood or behavior should be monitored as this drug may cause behavioral problems.

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