Lyrica pregabalin

Lyrica pregabalin

• Lyrica is a brand name of an active ingredient called pregabalin.
• Lyrica pregabalin is one of the most common medications in treatment seizures so it is known as an anticonvulsant medication.
• Also due to anti-anxiety effect, known as anxiolytic.

What are Lyrica pregabalin indications?

Due to its pharmacological activity, there are many indications:

• Certain types of seizures (anticonvulsant).
• Neuropathic pain: one of the diabetic complications causing severe nerve pain.
• Spinal cord injury associated with neuropathic pain.
• Postherpetic neuralgia: post herpes zoster infection.
• Fibromyalgia: as an alternative agent for a patient who does not respond or tolerate preferred agents.
• Generalized anxiety disorder.

What are the adverse effects of Lyrica pregabalin?

Lyrica pregabalin adverse effects:

 

• Blurred vision.
• Chest pain.
• Hypertension or hypotension.
• Contact dermatitis.
• Decreased libido.
• Abdominal pain.
• Weight gain.
• Dry mouth.

Most serious adverse effects, need to call your doctor immediately and stop medication:

• Severe allergic reaction.
• Severe dizziness.
• Trouble breathing.
• Suicidal attempt.
• Mental problems.
• Unusual change in your mood.

Lyrica pregabalin warnings and precautions:

Warnings and precautions of Lyrica pregabalin:

• Hypersensitivity: allergic reaction to Lyrica pregabalin, including skin redness, rash, dyspnea, and wheezing.
• Respiratory depression: which is a serious life-threatening condition. This risk increases with chronic obstructive pulmonary disease and in the elderly.
• Cardiovascular disease: Use with caution in heart failure patients.
• Renal impairment: use with caution and dosage adjustment is required.
• Peripheral edema: common adverse effect, so use with cautions in a patient with heart failure, and concomitant use of medications causing weight gain or peripheral edema.

Lyrica pregabalin and other medications interactions:

Revise all your medications before starting Lyrica pregabalin with your doctor.

Many drug-drug interactions may occur, so a dose adjustment may require.

Examples of these interactions:

Medications avoid concomitant use of pregabalin:

Medications decrease the effect of pregabalin:

Medications increase effects of pregabalin:

 

• Kava-kava.
• Magnesium sulfate.

Lyrica pregabalin may increase the effect of the following medications:

 

• CND depressants.
• Oxybate salt products.

Before starting Lyrica pregabalin:

You need to tell your doctor if you have one of the following medical conditions before starting Lyrica pregabalin:

• Heart problem: especially heart failure.
• Bleeding disorders: like thrombocytopenia (low platelets level).
• Lung disease: like a chronic obstructive pulmonary disease.
• Suicidal thoughts.
• Renal impairment.
• Drugs or alcohol abuse.
• Severe allergic and hypersensitivity reactions.

Things should be avoided during treatment with Lyrica pregabalin:

• Avoid driving.
• Avoid operate machinery.
• Avoid drinking alcohol.
• Avoid stopping Lyrica suddenly.
• Avoiding the use if you had a previous allergy history.

Special populations and use of Lyrica pregabalin:

There are many concerns of using Lyrica pregabalin in certain populations:

• Elderly: Lyrica should be used with caution in the elderly and dosage adjustment is required, so starting with the lowest dose is mandatory.
• Pediatric: Lyrica not approved in pediatric at age below 18.
• Pregnant: use of Lyrica in some cases may be necessary to control seizures, your doctor will help you to make a decision.
• Breast-feeding: it is not recommended to use Lyrica in breastfeeding.
• Renal impairment: use of Lyrica in renal impairment required specific dose adjustment according to the degree of impairment.
• Cardiac patients: use with caution especially with a congestive heart patient.

Lyrica pregabalin dosage and strengths:

Lyrica is available in many forms:

 

• Oral solutions.

Many strengths are available:

• Capsules: there are capsules contains 25mg, 50mg, 75mg, 100mg, 150mg, 200mg, 225mg, and 300mg.
• Oral solutions: 20mg/ml.
• Tablets: extended-release tablets 24 hour 82.5mg, 165mg, 330mg.

How to use Lyrica pregabalin?

• Take Lyrica by your mouth as your doctor’s instructions.
• You can use Lyrica with or without meals.
• You should swallow the whole tablet.
• You should not crush or chew tablets.
• You should take it at the same scheduled time.
• You should not stop the medication suddenly, need to tapper the dose under the supervision of your doctor.
• You should avoid drinking alcohol during use of Lyrica.
• You should store away from heat and light.
• If you missed dose, you should take it immediately. Only skipped if it is a time of the scheduled dose.

Lyrica pregabalin overdose:

Overdosing of Lyrica may cause by:

• Ingestion of too much dose.
• Concomitant use of medications increases the effects of Lyrica and may cause toxicity.

Overdosing signs and symptoms:

 

• Reduced consciousness.
• Trouble breathing.
• Heart block.

Call your doctor immediately and visit the emergency department of the nearest hospital.

Overdosing management:

Under the supervision of healthcare provider in hospital:

• induce emesis and gastric lavage.
• Maintain the airway.
• Monitoring vital signs.
• Lyrica may be removed by hemodialysis.
• There is no antidote for Lyrica.

Xanax symptoms

tablet description

Lyrica tablets