Tag: buy valium 5mg tablets
Diazapin
Diazapin
Diazapin is the street name for Diazepam which is known by the trade name Valium, so the first piece of advice we are going to offer you today, don’t buy diazepam from the streets, you have always to buy drugs from trusted sources, pharmacies, or trusted online websites such as pharmastores.
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So, what is Diazepam known in the streets as Diazapin?
Diazepam belongs to the benzodiazepines class of medication.
It is thought that diazepam works by enhancing the activity of specific neurotransmitters in the brain.
These neurotransmitters are known as GABA (Gamma-aminobutyric acid), they are responsible for calming the excitation of the CNS (Central Nervous System).
Uses and indications:
Diazepam in the streets called Diazapin is used to relieve anxiety which is affecting life.
It is used for relieving alcohol withdrawal symptoms including agitation.
Diazepam can be also used in addition to other medications to control muscle spasms and spasticity caused by some neurological disorders, such as cerebral palsy, paraplegia, athetosis, and stiff-man syndrome.
Cerebral palsy:
A group of disorders affecting movement and muscle tone may also affect posture.
It is caused by damage to the brain during development, mostly before birth.
Paraplegia:
An injury of the spinal cord or to the nerves at the end of the cauda equine (spinal canal), causing changes in the strength, sensation, and other body functions related to the site of injury.
Athetosis:
A movement dysfunction characterized by involuntary, continuous, slow, and rolling writhing movements.
Stiff-man syndrome:
A neurological disorder that is rare and characterized with features of an autoimmune disease.
It causes fluctuating rigidity in the muscles of the trunk and the limbs and increased sensitivity to stimuli, like noise, touch, and distress.
Diazepam may be used also as an adjunctive therapy to control seizures.
It is used to provide sedation before surgeries or any medical procedures.
Warnings:
Opioids are a class of painkillers, which help in controlling acute pain cases.
When they are used with Diazepam, they may slow or stop breathing leading to death.
That’s why the FDA (Food and Drug Administration) issued a black box warning about their use together.
The wrong use of diazepam may lead to overdose, addiction, or even death.
Overdose symptoms include:
- Bluish lips and nails
- Blurred or double vision
- Confusion
- Depression
- Dizziness
- Incoordination
- Excitability
- Weakness
- Breathing difficulties
- Unresponsiveness
- Deep sleep without the ability to rouse from it
- Coma like state
The use of diazepam is contraindicated in the following medical conditions.
- Myasthenia gravis (a disorder causing weakness of the muscles)
- Severe breathing problems
- Sleep apnea (the breathing stops during sleep for a short period)
- Narrow-angle glaucoma
- Uncontrolled case of open-angle glaucoma
- Severe liver disease
Seizures may be very dangerous with pregnancy, it may harm both mother and fetus, that’s why diazepam should not be stopped without orders from the doctor.
Dosage and administration:
Diazepam is taken exactly as the doctor prescribed, commit strictly to the exact dose and the exact times the doctor determined.
Before taking any medication, read the medication guide carefully, and follow it accurately.
If you have any misunderstood information, consult with your doctor or pharmacist about them.
This medication is prescribed just for you, don’t share it with others as it may be not suitable for them.
Measure the dose carefully with a special measuring device, not with the household spoons, if you are using the liquid form of Diazepam.
Diazepam is a drug that should be used for only 4 months, if you are going to use it for a longer period, the medical condition has to be reassessed periodically.
It should be stored at room temperature, far from moisture, heat, and light.
Cessation of diazepam suddenly may cause withdrawal symptoms, your doctor will decrease the dose gradually to avoid that.
Withdrawal symptoms:
- Abdominal cramps
- Headache
- Tremors
- Sweating
- Muscles pain
- Vomiting
- Severe anxiety
- Confusion
- Restlessness
- Insomnia (sleeping problem)
- Numbness
- Panic attacks
- Memory problems
- Weakness
- Decreased appetite
- Sensory hypersensitivity (hypersensitivity to light and noise)
- Heart palpitations
- Muscles twitching
More serious complications with higher doses or longer durations:
- Hallucinations
- Seizures
- Depersonalization
- Tingling in the arms and legs
- Delirium
- Psychosis
- Convulsions
- Coma
- Death
Interactions:
Using many drugs together may change the way any of them works, they may induce or inhibit the action of each other, and this may cause an increase in the side effects.
Alcohol and herbal products may also do the same.
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- MiraLAX (polyethylene glycol 3350)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Paracetamol (acetaminophen)
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
The above list contains some of the drugs interacting with diazepam.
Always buy your medications from trusted sources to avoid falling in counterfeit medicines such as diazapin.
Drug diazepam
Drug diazepam
Drug: drug means medicine that has a physiological effect happen when ingested or introduced to the body.
Diazepam: Diazepam is first marketed as valium, is considered a medicine of the benzodiazepine class of medications. And one of the best sellers medicine in this pharmacological class.
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Drug diazepam uses:
Drug diazepam has many indications you can use for it under the supervision of your doctors.
For examples:
- Anxiety: as antianxiety in acute and severe cases.
- Seizure: can be used alone or in combination with other medications.
- Alcohol withdrawal symptoms.
- Intoxication: the intoxication of certain substances like cocaine and sympathomimetics drugs.
- Serotonin syndrome.
- Hydroxychloroquine and chloroquine toxicity.
- Neuroleptic malignant syndrome.
- Muscle spasm, spasticity, and rigidity.
Drug diazepam adverse effect:
Before starting the use of diazepam your doctor will discuss with you the adverse effect that may happen during a treatment course.
This adverse effect if happen with you refers to your doctor deciding to continue or stop use diazepam.
you can buy diazepam from pharmastores
Common adverse effects:
- Dizziness and drowsiness.
- Slurred speech.
- Blurred vision.
- Abdominal pain.
- Muscle weakness.
- Memory loss.
- Dry mouth.
- Respiratory depression.
- Impaired motor mobility.
- Nasal congestion.
- Difficulty in urination.
- Skin rash, urticaria, pruritis.
- Allergic reaction and hypersensitivity.
- Elevated liver function enzyme.
- Nasal congestion.
Drug diazepam warning and precautions:
There is a list of medical conditions that have a concern to use diazepam in these situations and need to discuss with your doctor.
Examples of these conditions:
- Respiratory depression and other respiratory disorders.
- Severe hepatic impairment.
- Severe renal impairment.
- Hypersensitivity and allergic reactions to benzodiazepine group.
- Narrow angle-glaucoma.
- Abuse, misuse may cause physical dependence.
- Use other sedative medications with diazepam increases sedative effects.
From these conditions, some conditions are absolute contraindicated to use diazepam:
- History of allergic reaction with diazepam.
- If you have sleep apnea.
- If you suffer from respiratory depression or other respiratory disorders.
- If you have hepatic dysfunction.
- If you have narrow-angle glaucoma.
- If you have an autoimmune disease called myasthenia gravis disease which causes severe muscle weakness.
- If you are pregnant or planning.
Drug diazepam overdose:
Drug diazepam overdose means if you are treated with diazepam for a long duration and high dose, accidentally ingestion of high dose, or use concomitant medications increase the effect of diazepam due to interaction between them.
Signs and symptoms of overdose:
- Upset stomach.
- Low blood pressure.
- Respiratory depression.
Management of diazepam overdose:
- Maintain a clear airway.
- Treat hypotension (low blood pressure).
- Using activated charcoal.
- Monitoring of conscious level.
- Using activated charcoal.
- Use antidote: flumazenil (antagonize diazepam effect).
Drug diazepam misuse, abuse, and physical dependence:
Long-term use of diazepam with high doses leads to physical dependence.
Your doctor will adjust the dose for you and keep following with him until discontinuing diazepam.
Never stop diazepam suddenly or without refer to your doctor.
Withdrawal symptoms of diazepam:
- Headache
- Muscle pain, ang rigidity.
- Hypersensitivity, allergic reaction.
- Numbness and tingling of extremities.
Management of withdrawal symptoms:
In patients receiving extended or high doses of diazepam, you should tapper the total daily dose gradually under the supervision of your doctor.
Never stop diazepam suddenly.
Monitoring parameters you need to follow up during treatment by diazepam:
Keep watching the following:
- Heart rate.
- Respiratory rate.
- Blood pressure.
- Mental status.
- Complete blood count.
- Liver function test.
Call your doctor immediately if you feel:
- Increase severity of anxiety.
- Trouble sleeping.
- Panic attacks.
- Change in behavior and moods.
- Thoughts about suicide.
- Excessive increase in activity and talking.
You should not do the following once start diazepam:
- You should not drive.
- You should not operate machinery.
- You should not take other sedative medications.
- You should not discontinue diazepam suddenly.
- You should not drink alcohol.
- Never to used diazepam if you are pregnant.
- Never use diazepam if you are breastfeeding.
- You should not use diazepam for a long duration.
- Never use diazepam if you age over 56years.
- Never advise anyone to use diazepam without doctor consultation.
Concern about the use of diazepam in a special group of populations:
- Elderly: use is contraindicated at age over 65 years, otherwise use with the lowest effective dose which may increase gradually.
- Pregnancy: absolute contraindicated to use diazepam in pregnancy or planning as their adverse effects on the fetus.
- Breastfeeding: diazepam secreted in milk so avoid use during breastfeeding.
- Psychotic: diazepam is contraindicated in the psychotic patient.
- Pediatric: never use diazepam in the pediatric population at age below 6months otherwise use under the supervision of a doctor in a specific dose.
Food and drink should avoid using with diazepam:
- Alcohol: as alcohol has a sedative effect that will increase by diazepam so a concomitant use should be avoided.
- Grapefruits: drinking or eating grapefruits interact with diazepam, increase its effectiveness and adverse effects.
Taking valium for MRI
Taking valium for MRI
When you seek a doctor’s help to diagnose a certain health condition, you will be asked to undergo some medical procedures such as CT scan, MRI scan, ultrasound, X-ray, and breast biopsy.
Is there any benefit from taking Valium for mri?
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But first, what is meant by MRI?
Magnetic resonance imaging (MRI) is a type of scan that uses a large magnet and radio waves to create detailed images of the organs and tissues inside the body.
MRI is one of the safest imaging techniques available because, unlike X-ray or CT scans, MRI doesn’t use any ionizing radiation.
Composition of MRI scanner:
An MRI scanner is composed of a large tube containing powerful magnets, the patient lies inside the tube during the scan.
MRI scan is used to examine almost any part of the body including:
- Brain and spinal cord.
- Bones and joints.
- Heart and blood vessels.
- Internal organs such as the liver and prostate gland.
MRI scan results are very helpful in diagnosing the disease, planning the treatments, and determining how effective the previous treatment was.
What happens during the MRI scan?
During an MRI scan, the patient lies on a flatbed, this bed will later be moved into the scanner.
Depending on the part of the body needed to be scanned, the patient will be moved into the scanner with the head or feet first.
The scanner is operated by a well-trained radiographer using a computer in a different room.
An electric current in the scanner coils will be turned on and off producing a loud tapping noise, you will be given earplugs to wear.
During the MRI scan, the patient is asked to keep as still as possible to get a detailed and accurate image.
The time of the scan varies from 15 to 90 minutes depending on many aspects as the size of the area scanned and how many images are taken.
MRI scan is not recommended in certain conditions such as:
- Pregnancy and breastfeeding: although it’s thought that it is safe to use an MRI scan in later pregnancy (after 3 months), it is not well-known whether the strong magnetic fields have long-term harms on the developing baby or not.
- Metal implants such as:
- Metal plates, wires, or screws for bone fractures.
- Nerve stimulator.
- Drug pump implant.
- Eye implants.
- Intrauterine device (IUD).
- Dental fillings and tattoos.
Many patients experience anxiety during an MRI scan. This is because of the noise generated from the scanner; also the anxiety may be a symptom of claustrophobia in some cases.
Some tips for relaxing rather than taking Valium for mri:
- Listen to music or wear an earplug.
- Try to control your stress by controlling your breathing, inhale through the nose and exhale slowly out of the mouth.
- Close your eyes and imagine you are on a wide sandy beach for example.
What is Claustrophobia?
An anxiety disorder where the person experiences a fear of enclosed spaces, restrictions, or suffocation.
About 20% of patients undergoing MRI scans can’t complete the procedure due to claustrophobia.
The symptoms may be mild and easily handled, or severe and characterized by at least four of the following:
- Chest pain.
- Chocking sensation.
- Fear of dying.
For severely distressed
For severely distressed or pre-determined claustrophobic patients, a short-acting sedative or anti-anxiety agent can be prescribed before the procedure.
Among many sedative medications, a benzodiazepine drug such as Valium is a great choice for moderate anxiety prior to an MRI examination.
Taking Valium for mri to relieve anxiety will enhance the effect of GABA (a certain neurotransmitter in the brain) which suppresses nerve activity.
For more severe symptoms related to claustrophobia, taking Valium for mri may be combined with an opioid medication (mainly prescribed for pain and sedation).
The patient should talk with an expert and list all the medications taken within the last few days before going through the MRI scan.
Some side effects arise due to taking Valium for mri such as:
- Loss of equilibrium.
- Sleep disturbance.
Avoid these before taking Valium for mri:
- Drinking alcohol.
- Grapefruit juice.
After the scan, you can resume your normal daily activities immediately, unless you have had a sedative.
In this case, a friend or a family member should drive you home and observe you for the first 24 hours.
It is not safe to drive or drink alcohol for 24 hours after taking Valium for mri.
Before you undergo an MRI scan, talking freely with the healthcare provider and asking any question, and sharing with him/her your fears from the examination will greatly help you with your examination.
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Diazepam tab 10mg
Diazepam tab 10mg
Diazepam tab 10mg, one of the best seller medications of the benzodiazepine group.
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Benzodiazepine is a pharmacological group contain diazepam, alprazolam, clonazepam, and others.
Benzodiazepines act by working in neurotransmitters in the brain, these neurotransmitters suppress the activity of nerves.
Indications of diazepam tab 10mg:
- Anxiety: acute or severe anxiety as monotherapy or adjunctive therapy.
- Hydroxychloroquine/chloroquine toxicity: in severe cases.
- Intoxication: cocaine, methamphetamine, and other sympathomimetics.
- Muscle spasm, spasticity, and/ or rigidity.
- Neuroleptic malignant syndrome: for management of muscle rigidity or anxiety in patients with severe symptoms.
- Serotonin syndrome: serotonin toxicity.
- Substance withdrawal: alcohol withdrawal syndrome.
Adverse effects of diazepam tab 10mg:
During treatment by diazepam tab 10 mg your doctor will advise you to keep alert if abnormal symptoms appear on you, these symptoms like:
- Abdominal pain.
- Muscle weakness.
- Memory loss.
- Dry mouth.
- Respiratory depression.
- Impaired motor ability.
- Nasal congestion.
- Difficulty in urination.
- Skin rash, urticaria, pruritis
- Trouble in speaking.
- Blurred vision.
- Allergic reaction.
- Elevated liver function enzyme.
- Increase appetite.
Your doctor will advise you before start using Diazepam tab 10mg to do/ or not the following:
- Do not drink alcohol.
- Do not drive.
- Do not operate machinery.
- Do not use another benzodiazepine drug.
- Do not use diazepam if you age over 65years.
- Do not stop diazepam suddenly without referral to your doctor.
- Do not use diazepam for a longer duration.
- Do not advise the use of diazepam for anyone his/her symptoms seem to be yours.
- Do not use diazepam if you are pregnant or planning.
- Do not use diazepam if you are breastfeeding.
- Check with your doctor all your prescribed, non-prescribed medications.
Also, there are medical conditions in that diazepam are considered to be contraindicated and your doctor should know about it:
- if you have narrow-angle glaucoma.
- If you have severe renal disease.
- If you have severe hepatic disease.
- If you have respiratory disorders.
- If you suffer from sleep apnea.
- If you have a history of diazepam allergy or another benzodiazepine allergy.
- If you are pregnant or planning.
- If you have myasthenia gravis disease (autoimmune disease affecting muscle cause muscles weakness).
Warnings and precautions of use Diazepam tab 10mg:
Diazepam 10 mg tablet as other medications, there are warnings and precautions about its use. These warnings and precautions were written in the leaflet.
Warnings and precautions like:
- Respiratory depression.
- Severe hepatic impairment.
- Severe renal impairment.
- Allergic and hypersensitivity reactions.
- Narrow angle-glaucoma.
- Abuse, misuse may cause physical dependence.
- Sedations especially if you take other sedative medications.
special consideration for using diazepam in special populations:
- Elderly: used by the lowest effective dose then titrate according to tolerability, at age over 65years use is contraindicated.
- Pregnancy: contraindicated to use diazepam.
- Breast-
- feeding: contraindicated to use diazepam.
- Psychotic disorder: contraindicated to use in a psychotic patient.
- Pediatric populations: can be used in specific doses but contraindicated below 6 months of age.
Medications should be a concern when used in concomitant with diazepam tab 10mg:
Concern about drug-drug interaction with diazepam, your doctor will modify your dose according to interaction.
- Drugs avoid use during treatment with diazepam:
- Fusidic acid.
- Oxybate salt products.
- Drugs decrease the effect of diazepam:
- Theophylline derivatives.
- Drugs increase the effect of diazepam:
- Chlorphenesine carbamate.
You should monitor the following parameter during the use of diazepam tab 10mg:
- Heart rate.
- Blood pressure.
- Respiratory rate.
- Mental status.
- Complete blood count.
- Liver function test.
You should call your doctor if you feel the following symptoms:
- Trouble sleeping.
- Agitated or restless.
- Anxiety or worsening of anxiety.
- Panic attacks.
- Change in behavior and mood.
- Thoughts about suicide.
- Excessive increase in activity and talking.
What happens if you take diazepam tab 10mg overdose?
Diazepam overdose:
Long duration treatment of diazepam, using higher doses, concomitant use of medications increases the activity of diazepam, or accidental ingestion of higher dose, all that increase risk of overdose and toxicity.
Diazepam overdose symptoms:
- Muscle weakness.
- Blurred vision.
- Low blood pressure.
- Upset stomach.
- Respiratory depression.
Treatment of diazepam overdose:
- Using activated charcoal.
- Maintain a clear airway.
- Management of hypotension.
- Monitor level of consciousness.
- Use antidote: flumazenil.
Diazepam withdrawal symptoms:
In patients receiving extended or higher-dose diazepam, you should taper the total daily dose gradually to avoid withdrawal symptoms.
Even your doctor will advise you not to discontinue medication suddenly.
Symptoms of withdrawal effect of diazepam:
- Muscle pain, cramps.
In severe cases you may feel:
- Numbness and tingling of extremities.
Diazepam normal dosage
Diazepam normal dosage
Why did we say diazepam normal dosage, not diazepam normal dose? Is there a difference between dosage and dose?
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People usually say dosage or dose interchangeably without differentiating between them.
So, what is meant by dosage, and what is meant by dose?
According to the American Medical Association (AMA), the dose is the specific amount of medication taken at one time; however, the dosage is the prescribed amount, number, and frequency of doses over a specific period.
So, what is the diazepam’s normal dosage?
First, let’s know what is diazepam? To which family of drugs does it belong? And how it works?
Diazepam is a member of many members of a family known as benzodiazepines and sometimes called benzos.
The benzodiazepines family contains many drugs, such as alprazolam, clonazepam, and diazepam our title for today.
They raise the level of the GABA neurotransmitter in the brain which is an inhibitory neurotransmitter, helping to calm or sedate the patient, and that’s the same way diazepam and other members of the family work.
Diazepam normal dosage:
Before taking diazepam, read the medication guide carefully, and discuss it with your health care provider to avoid any misunderstandings and misuse of the drug.
Take this medication exactly as your doctor prescribed.
If you are going to use the liquid form of diazepam, use a special measuring device or a graduated syringe, but don’t use the household spoons to make sure you took the correct dose.
The medical condition should be reassessed regularly if you are going to use diazepam regularly.
Diazepam may cause addiction especially if used with high doses for a long time, that’s why you should take it exactly with the dose and for the exact duration the doctor determined.
Don’t take diazepam with alcohol, as it may increase the inhibitory effects of the CNS (Central Nervous System), such as drowsiness and dizziness.
Avoid taking grapefruit or its juice while taking diazepam, as grapefruit increases the blood levels of diazepam.
The doctor prescribes the dose based on the kind of medical condition, its severity, age, and weight of the patient.
However, diazepam’s normal dosage is determined for each medical condition.
Diazepam normal dosage:
For adults:
Anxiety
Orally or IV/IM injection from 2 to 10 mg every 6 to 12 hours, the dose should not exceed 30 mg every 8 hours
Alcohol withdrawal
Orally 10 mg every 6 to 8 hours on the first day, reduced to 5 mg every 6 to 8 hours
IV/IM injection starts with 10 mg, then additional doses from 5 to 10 mg every 6 to 8 hours as needed
Endoscopy
IV injection of 10 mg titrated immediately before the procedure and no more than 20 mg cumulatively
Don’t forget to reduce the dose of narcotics by one third
IM injection from 5 to 10 mg 30 minutes before the procedure
Preoperative sedation
IM injection of 10 mg before surgery
Sedation in the ICU (Intensive care unit)
IV injection from 5 to 10 mg 1 to 2 hours before surgery and then 0.03 to 0.1 mg per Kg every 30 minutes to 6 hours
Muscle spasms
Orally from 2 to 10 mg every 6 to 8 hours
IV/IM injection starts from 5 to 10 mg and then every 3 to 4 hours if necessary
Status epilepticus
IV/IM injection from 5 to 10 mg every 5 to 10 minutes, no more than 30 mg for a total dose
Parenteral solution of 0.5 mg/Kg and then 0.25 mg/Kg in 10 minutes
For pediatrics
It is not used for patients less than 6 months
In patients younger than 6 years: no more than 0.5 mg/Kg
Sedation and muscle relaxation
In patients older than 12 years:
Orally from 0.12 to 0.8 mg/Kg/day divided every 6 to 8 hours
IV/IM injection from 0.04 to 0.2 mg/Kg every 2 to 4 hours, no more than 0.6 mg/Kg in 8 hours
Status epilepticus
Using parenteral solution
From 2 to 6 years: 0.5 mg/Kg, and it may be repeated from 4 to 12 hours
From 6 to 12 years: 0.3 mg/Kg, and it may be repeated from 4 to 12 hours
In patients older than 12 years: 0.2 mg/Kg, and it may be repeated from 4 to 12 hours
Using IV injection
From 6 months to 5 years: from 0.2 to 0.5 mg initially, and then repeated every 2 to 5 minutes and no more than 5 mg which may be repeated 2 to 4 hours later
In patients older than 5 years: 1 mg slowly every 2 to 5 minutes, no more than 10 mg which may be repeated after 2 to 4 hours if necessary
Geriatrics:
Orally from 2 to 2.5 mg every day or every 12 hours initially and it may be increased gradually
And lower doses should be used with rectal gels
Dosage modifications:
With patients suffering from hepatic impairment 50% only of the dose should be used
However, diazepam normal dosage should not be used all the time and individualized dosage should be used.
1 mg Valium
1 mg Valium
A drug is a chemical substance that can be used for diagnosis, prevention, and treatment of disease and the drug is usually available in many dosage forms.
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A dosage form of a drug is designed for administration by a suitable method for the patient by different routes, they are pharmaceutical preparations or formulations that contain a specific mixture of medical substances and excipients (inactive components) to provide easy, and accurate administration, and delivery of the drug.
The drug is usually available in many dosage forms, tablets, capsules, oral solutions, intramuscular, and intravenous injections, rectal gels, and others.
Valium is one of these drugs available in many dosage forms; one of these forms is 1 mg Valium that is available in oral solution form.
What is Valium?
1 mg Valium is a diazepam drug belonging to the medicinal family benzodiazepines.
It increases the activity of certain neurotransmitters GABA (gamma-aminobutyric acid), a specific neurotransmitter that sends signals throughout the nervous system.
No enough GABA means an excited state of the body causing anxiety, muscle spasms, and seizures.
When you take 1 mg Valium, you will have more GABA, decreasing anxiety, muscle spasms, and seizures.
Uses and indications:
1 mg Valium is used in the following medical conditions,
- anxiety
- alcohol withdrawal symptoms
- add-on medication for skeletal muscle spasms
- add-on medication for some types of seizures
Side effects:
As 1 mg Valium slows down the brain’s activity, it may interfere with judgment, thinking, and motor skills.
More common side effects
- drowsiness
- tiredness
- fatigue
- weakness of muscles
- ataxia (inability to control the muscle movements)
- headache
- tremor
- dizziness
- dryness of the mouth or excessive salivation
- nausea
- constipation
These side effects may be mild and going from their own, and maybe severe that need medical attention.
Serious side effects
- worsening of seizures either in number or severity
- Mental changes such as
- depression
- confusion
- vertigo (spinning sensation)
- slurred speech
- double or blurred vision
- suicidal thoughts
- memory loss
- recreational reactions such as
- extreme excitement
- anxiety
- hallucinations
- worsening of muscle spasms
- sleeping troubles
- agitation
- liver problems such as jaundice (yellow skin and yellow eyes)
- Bladder problems such as difficulty in urination or difficulty in holding urine
- decrease or increase in sex drive
Dosage and administration:
The dosage determination depends on several factors including,
- the type and severity of the medical condition
- the age of the patient
- the used dosage form
- other medical conditions
Usually, the doctor starts on a low dosage and then adjusts it over time to reach the smallest dose being effective and safe.
As 1 mg Valium is available in oral solution form, you must take it with specific measuring devices or with the measuring syringe provided with the drug.
Don’t use the household spoons, as they may lead to incorrect doses.
Commonly prescribed doses:
Child (0 – 5 months):
The drug didn’t be studied at this age, so it is not recommended for use at this age.
Dosage for anxiety, muscle spasms, and seizures
Adults (18 – 64 years):
The standard dose is 2 mg to 10 mg 2 or 4 times a day
Childs (6 months – 17 years):
The standard dose is 1 mg to 2.5 mg 3 to 4 times a day
Seniors (65 years and older):
The standard dose is 2 mg to 2.5 mg 1 to 2 times a day
Patients with debilitating disease:
The standard dose is 2 mg to 2.5 mg 1 to 2 times a day
Dosage for alcohol withdrawal
Adults (18 – 64 years):
The standard dose is 10 mg 3 to 4 times during the first day, then the doctor will reduce the dose t 5 mg 3 to 4 times a day based on symptoms of withdrawal
Childs (6 months – 17 years):
The standard dose is 1 mg to 2.5 mg 3 to 4 times a day
Seniors (65 years and older):
The standard dose is 2 mg to 2.5 mg 1 to 2 times a day
Patients with debilitating disease:
The standard dose is 2 mg to 2.5 mg 1 to 2 times a day
If you miss a dose, take it when you remember, but don’t take it with the next dose, taking too much leads to overdose symptoms.
Overdose symptoms:
- labored respiration
- fatigue and sleepiness
- behavior incoordination
- inability to be alert
- Blue skin, lips, and nails
- Double or blurred vision
- abdominal pain
- weakness
- drowsiness
- very low blood pressure
- coma
If you felt any of these symptoms, call an ambulance or go to the nearest hospital.
1 mg Valium should not be stopped at once; it should be withdrawn gradually to avoid withdrawal symptoms.
Withdrawal symptoms:
- tremors
- stomach pain
- muscles cramps
- vomiting
- sweating
- headache
- extreme anxiety
- tension
- restlessness
- confusion
- irritability
- hallucinations
- seizures
Discuss the information in this article with your health care provider.
Medical uses for Valium
Medical uses for Valium
Valium (diazepam) is a benzodiazepine drug that works by enhancing the activity of certain neurotransmitters in the brain.
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Classification of benzodiazepine family according to the duration of action:
- Very short-acting such as triazolam.
- Short-acting such as lorazepam.
- Long-acting such as Valium.
Medical uses for Valium:
The main use of Valium is to treat anxiety disorders, muscle spasms, and alcohol withdrawal symptoms.
It is also used in combination with other drugs to treat certain types of seizures.
Valium is sometimes used to induce sleep and relaxation in patients before operations or dental treatments. This is known as (pre-med).
Usual doses prescribed when seeking medical uses for Valium:
- Anxiety: 2 mg 3 times a day.
- Muscle spasms in adults: 2 mg to 15 mg a day, this dose can be increased up to 20 mg a day if required.
- Muscle spasms in children: (from 1 month to 17 years ):
The dose varies according to age, usually given twice a day with a 10 to 12 hours gap between each dose.
The dose will be lowered for the elderly (above 65 years) or patients with liver diseases, kidney, or severe breathing problems.
You should not use Valium if you have:
- Severe breathing problems.
- Myasthenia gravis (muscle weakness).
- Sleep apnea (stopping breathing during sleep).
- Narrow-angle glaucoma.
- Uncontrolled open-angle glaucoma.
- Severe hepatic deficiency.
- Allergic reactions towards the drug or any of the ingredients.
- Over 65 years old.
- Arteriosclerosis (a condition that causes a decrease in the blood flow to the brain).
- Low levels of a certain protein in the blood called albumin.
To ensure you are safe and have benefited from the medical uses for Valium tell your doctor if you have ever suffered from:
- Breathing problems.
- Kidney or liver diseases.
- Drug or alcohol addiction.
- Suicidal thoughts, depression, or mood disorder.
Some side effects that arise due to using this drug for the medical uses for Valium:
- Severe drowsiness.
- Mood or behaviour changes.
- Suicidal thoughts.
- Hallucinations or confusion.
- Muscle weakness.
- Problems with balance.
- Tremors (shaky hands).
- Shallow or slow breathing.
- Amnesia (difficulty in remembering things).
- Felling aggressive or irritable.
Some medications interfere with the way of action of Valium, causing an increase in the chance of serious side effects:
Ask your doctor or a pharmacist before taking Valium if you are taking:
- Anticonvulsants (to treat epilepsy).
- Hypnotics (to treat sleep problems).
- Sedating antihistamines such as promethazine.
- Strong pain killers such as codeine or tramadol.
- HIV medicines such as ritonavir.
- Antifungal medicines such as fluconazole.
- Proton pump inhibitors (medicines used to decrease stomach acid) such as omeprazole.
- Muscle relaxants such as tizanidine.
- Medicines to treat bacterial infections as rifampicin.
- Medicines for asthma and other breathing problems such as theophylline.
- Oxybate salts.
- Magnesium sulfate.
Pregnancy and breastfeeding:
There is no enough information about the safety of taking Valium in pregnancy. However, it is not recommended to take Valium for medical uses Valium during pregnancy as the newborn baby may show withdrawal symptoms.
Ask a doctor’s help to recommend a safer drug during pregnancy.
Valium may be used during breastfeeding as long as it is used at a low dose occasionally or for a very short time.
If you use Valium for a long time or in high doses during lactation, it will pass into breast milk causing the baby to be tired or drowsy and highly affect his/her feeding.
General precautions:
- Never share this medicine with any person, especially with people with a history of drug abuse or addiction.
- While seeking the medical uses for Valium, be sure that you are using the drug for a short time.
Using this drug for a period longer than 4 weeks will subject you to the risk of tolerance and dependence.
- This medicine is not to be stopped suddenly; this will increase the seizures and undesired withdrawal symptoms.
Some signs of Valium overdose:
- Double vision.
- Trouble breathing.
- Uncoordinated movement.
- Slow or irregular heartbeats.
- Persistent drowsiness.
- Memory loss.
- Blood in urine or stool.
- Sleeping problems.
Ways of treatment of Valium overdose:
Closely monitor the following parameters: heart rate, blood pressure, liver enzymes, and mental health conditions.
Signs of addiction to Valium include:
- Isolation from family and friends.
- Loss of interest in once enjoyable
- Ignoring obligations.
- Continued use despite warnings and problems caused by the drug.
Mixing Valium with herbal supplements:
There is no evidence that it is safe to mix Valium with herbal medicines to benefit from the medical uses for Valium, this combination is found to cause a fatal increase in the drowsy effect of Valium.
You should avoid the following while using Valium:
- Operating machinery.
- Using opioids.
- Drinking alcohol.
Any side effect of the drug should get better within a few days; if the symptoms don’t improve speak to a doctor as you may need a lower dose.
Before you intend to buy Valium, you must be sure that you are buying the drug from trusted websites, or licensed online pharmacies as pharmastores
Which is better for back pain Flexeril or Diazepam
Which is better for back pain Flexeril or Diazepam?
Back pain is one of the most irritating problems in the world; it is also one of the most common reasons for a doctor’s visit, missing work, and a leading reason for disability in the world.
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Dealing with back pain starts with prevention going to simple home remedies ending with medications to manage the pain and function properly.
Which is better for back pain Flexeril or Diazepam?
Before taking any of them, you have to know when to see a doctor get a prescription for any of them.
- The pain is persisting for a few weeks
- The pain is severe and not improving with rest
- The pain is spreading down to the legs, especially if it is extending below the knee
- The pain is causing weakness, numbness, or tingling in the legs
- The pain is accompanied by loss of weight
Back pain can be a sign of a serious medical problem in some rare cases, seek immediate medical help if the back pain is,
- causing bowel or bladder problems
- accompanied by fever
- following a fall or other injury
Causes:
Back pain may be as a result of a fall or an injury, or may be linked to a medical condition such as,
- The strain of muscles or ligaments, the strain happens due to lifting a heavy object or a sudden awkward movement
Constant strains of the back can cause painful spasms especially if you are in a poor physical condition
- Bulging or ruptured disks, is bulging or rupturing to the soft material inside the disk, causing pressure on the nerve
- Arthritis, inflammation of the joints in the spine, causing lower back pain, including osteoarthritis
- Osteoporosis, painful fractures in the spine’s vertebrae when they become porous and brittle
Which is better for back pain Flexeril or Diazepam?
Flexeril containing the active constituent cyclobenzaprine HCl, working by blocking the nerve impulses sent to the brain.
This makes Flexeril be used to treat skeletal muscle conditions such as pain, injury, or spasms.
It should be in use in combination with rest and physical therapy.
Diazepam is a benzodiazepine drug, works by inducing the activity of certain neurotransmitters in the brain.
So, diazepam can be used as adjunctive therapy in muscle spasms.
Diazepam can be also used for several medical conditions, like anxiety disorders, alcohol withdrawal symptoms, and may be used also with other medications to control seizures.
Which is better for back pain Flexeril or Diazepam?
That’s according to the other drugs you are taking, both of them are contraindicated with several medications.
For Flexeril:
Contraindicated drugs
- isocarboxazid
- phenelzine
- safinamide
- tranylcypromine
Serious interactions – use alternative
- abametapir
- almotriptan
- amitriptyline
- amoxapine
- benzhydrocodone/acetaminophen
- bupropion
- calcium/magnesium/potassium/sodium oxybates
- citalopram
- clomipramine
- desipramine
- desvenlafaxine
- doxepin
- duloxetine
- eletriptan
- escitalopram
- fluoxetine
- fluvoxamine
- frovatriptan
- givosiran
- hydrocodone
- imipramine
- levomilnacipran
- linezolid
- meperidine
- methylene blue
- metoclopramide intranasal
- milnacipran
- mirtazapine
- naratriptan
- nefazodone
- nortriptyline
- paroxetine
- pramlintide
- protriptyline
- rizatriptan
- sertraline
- sodium oxybate
- sufentanil SL
- sumatriptan
- sumatriptan intranasal
- tedizolid
- tramadol
- trazodone
- trimipramine
- vandetanib
- venlafaxine
- verapamil
- vilazodone
- vortioxetine
- zolmitriptan
For Diazepam:
There are no contraindicated drugs with diazepam, but there are drugs casing serious interactions.
Serious interactions – use alternative
- abametapir
- apalutamide
- benzhydrocodone/acetaminophen
- calcium/magnesium/potassium/sodium oxybates
- carbamazepine
- cimetidine
- clarithromycin
- darunavir
- erythromycin base
- erythromycin ethylsuccinate
- erythromycin lactobionate
- erythromycin stearate
- fedratinib
- fexinidazole
- hydrocodone
- idelalisib
- ivosidenib
- ketoconazole
- lonafarnib
- metoclopramide intranasal
- mifepristone
- nefazodone
- rifabutin
- rifampin
- selinexor
- sodium oxybate
- St John’s Wort
- sufentanil SL
- tipranavir
- tucatinib
- valerian
- voxelotor
Both Flexeril and diazepam interact with alcohol and other CNS depressant drugs (Central Nervous System), like narcotics, sleeping pills, muscle relaxants, or anti-anxiety medicines.
Using them together causes severe drowsiness and dizziness.
Which is better for back pain Flexeril or Diazepam?
Well, let’s look at the side effects of both of them.
First, similar side effects, including dry mouth, blurred or double vision, drowsiness, dizziness, fatigue, tiredness, nausea, constipation, or muscle weakness.
Different side effects:
For Flexeril
Dry throat, headache, loss of appetite, stomach pain, diarrhea, or gases.
For Diazepam
Vertigo (a sensation that the world is spinning around you), loss of balance, memory problems, restlessness, irritability, drooling, speech problems, skin rash, itching, or libido (loss of interest in sex).
Which is better for back pain Flexeril and Diazepam?
Before taking any of them, we have to discuss some warnings.
For Flexeril
Flexeril is not used if the patient suffers from a thyroid disorder, heart block, congestive heart failure, a heart rhythm disorder, or if he had recently had a heart attack.
It is not used in patients younger than 15 years old.
For Diazepam
Diazepam is not used if the patient suffers from myasthenia gravis (muscle weakness), a severe breathing problem, sleep apnea (shortstop of breathing during sleep), narrow-angle glaucoma, uncontrolled open-angle glaucoma, two eye disorders, and severe liver disease.
It is not used for patients younger than 6 months old.
Finally, always consult with your doctor about the proper treatment that can be used for your specific medical condition.
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Diazepam 25 mg
Diazepam 25 mg
Have you ever heard about diazepam with a concentration of 25 mg?
The maximum dose we know is the rectal gel form with the concentration of 20 mg, till came the breakthrough of West-Ward Pharmaceuticals Corporation when they came out with Diazepam 25 mg in Diazepam Intensol Oral solution which contains 25 mg per 5 ml.
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Diazepam 25 mg is a benzodiazepine that has anti-anxiety, sedative, muscle-relaxant, anticonvulsant, and amnestic effects.
It works on the brain, on a certain type of transmitters, called GABA (Gamma-aminobutyric acid), which helps in the inhibition of the excessive activity of the Central Nervous System (CNS).
Indications:
Diazepam 25 mg is indicated for anxiety disorders and anxiety symptoms.
When we say anxiety, we don’t mean the daily anxiety coming from work or family, but we mean that type that is affecting our daily life and preventing us from doing our normal activities in a normal way.
Diazepam is also indicated in the symptomatic relief of alcohol withdrawal, like acute agitation, tremor, impending or acute delirium tremens, and hallucinosis.
It is used as adjunctive therapy for the relaxation of skeletal muscle spasms happening due to reflex spasms to local pathologies, such as inflammation of the muscles or joints, or it happens as a result of trauma.
Muscle spasms may also be a result of spasticity caused by upper motor neuron disorders, such as cerebral palsy (a group of disorders affecting the ability of the patient to move and maintain balance and posture) and paraplegia (a type of paralysis affecting the ability to move the lower half of the body), athetosis (slow, involuntary, and writhing movements of a group of muscles including the limbs, face, neck, tongue, and others), and stiff-man syndrome (a rare neurological syndrome with features of autoimmune disease).
Diazepam 25 mg may be also used adjunctively in convulsive disorders.
Diazepam is not intended for use for more than 4 months, that’s why the effectiveness and safety should be reassessed regularly by your physician.
Contraindications:
Diazepam 25 mg is contraindicated to be used in patients with known hypersensitivity to this active constituent.
It is contraindicated also in pediatrics under 6 months as there is no sufficient clinical experience for the use of diazepam in this age.
Diazepam should not be used in patients suffering from myasthenia gravis (weakness of muscles), severe respiratory insufficiency, severe hepatic impairment, and sleep apnea (breathing stops for a short period during sleep).
It may be used in patients with a controlled case of open-angled glaucoma, but may not be used with acute narrow-angled glaucoma.
Warnings:
Why did the FDA (Food and drug administration) issued a black box warning about using diazepam 25 mg with opioids?
Due to observational studies, the concomitant use of opioids and benzodiazepines was found to increase drug-related mortality, especially when compared with the use of opioids alone.
Using them together results in profound sedation, respiratory depression, coma, and death.
That’s why using opioids in combination with diazepam 25 mg is limited when alternatives are inadequate.
Why diazepam 25 mg can’t be given to patients with a history of substance abuse?
Using diazepam 25 mg may lead to misuse, abuse, and addiction.
This may cause overdosing which may lead to death.
Overdosing may be illustrated in the following symptoms:
- Extreme drowsiness
- Loss of balance or coordination
- Limp or weak muscles
- Slow breathing
- Coma which may eventually lead to death
Using diazepam 25 mg for a long time may cause withdrawal symptoms while stopping the drug.
Stopping the take of diazepam should be done gradually and under the supervision of a doctor to avoid withdrawal symptoms such as,
- Abdominal cramps
- Headache
- Tremors
- Sweating
- Muscles pain
- Vomiting
- Severe anxiety
- Confusion
- Restlessness and Insomnia (sleeping problems)
- Numbness
- Panic attacks
- Memory issues
- Weakness
- Reduced appetite
- Sensory hypersensitivity (high sensitivity to stimulation of the senses)
- Heart palpitations
- Muscle twitching
More serious symptoms including:
- Hallucinations
- Depersonalization
- Seizures
- Delirium
- Psychosis
- Convulsions
- Coma
- Death
Taking diazepam 25 mg with other drugs may also lead to undesirable side effects that may be serious.
Serious – use alternative
- abametapir
- apalutamide
- benzhydrocodone/acetaminophen
- calcium/magnesium/potassium/sodium oxybates
- carbamazepine
- cimetidine
- clarithromycin
- darunavir
- erythromycin base
- erythromycin ethylsuccinate
- erythromycin lactobionate
- erythromycin stearate
- fedratinib
- fexinidazole
- hydrocodone
- idelalisib
- ivosidenib
- ketoconazole
- lonafarnib
- metoclopramide intranasal
- mifepristone
- nefazodone
- rifabutin
Pregnancy:
Using benzodiazepines during pregnancy is associated with an increased risk of congenital malformations and other developmental abnormalities.
Respiratory and feeding difficulties have been reported with the use of diazepam 25 mg during pregnancy.
Nursing mothers:
Diazepam was proved to pass into breast milk. Therefore, breastfeeding is not recommended while using diazepam.
Diazepam 25 mg is characterized to be in an oral solution form, which makes it easier to be taken, with the higher concentration allowing the patient to take less amount for fewer times.
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How long is diazepam in your system
How long is diazepam in your system?
When does the drug start to work? When does it start to give the intended effect? Then, when does this effect fade?
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All of this happens depending on how fast does your body absorbs the medication? How does the body distribute it? How the body breaks it down?
Some medications like antihypertensive drugs (drugs used to lower your high blood pressure), such as metoprolol, work on the same day they are taken in, also, H2 blockers (drugs used to treat heartburn by blocking the cells responsible for secreting the stomach’s acid), such as famotidine.
However, other medications take a longer time to work, such as statins used for lowering the cholesterol levels, like atorvastatin, which may take from two to four weeks.
A drug like Sertraline, a medication used to treat depression; it may take up to months to give the full effect.
So, how long is diazepam in your system?
Diazepam is a benzodiazepine, working on certain neurotransmitters in the brain; these neurotransmitters are called GABA (Gamma amino-butyric acid), which produces a calming effect on the brain and nerves.
What is diazepam used for?
Diazepam is helpful in the management of anxiety symptoms, alcohol withdrawal symptoms, and seizures.
It is also used in the relaxation of muscle spasms and to provide sedation before surgeries or in the ICU (intensive care unit).
How to use diazepam?
Before taking any medication, read the medication guide provided with the drug carefully, and ask your health care provider about any information that you can’t fully understand.
Take diazepam exactly as prescribed by your doctor, and don’t share it with others.
The doctor determines the dose according to the severity of the medical condition, age, and weight of the patient.
However, there are regular doses for each medical condition it is used to treat.
Anxiety
2 to 10 mg orally or by intravenous/intramuscular injection 2 to 4 hours per day
Maximum dose: 30 mg 3 times per day
Alcohol withdrawal
10 mg orally 3 to 4 times during the first day, then the dose is decreased to 5 mg 3 to 4 times per day
If you are going to use the intravenous/intramuscular, 10 mg is a used, then an additional dose of 5 to 10 mg 3 to 4 times if needed
Endoscopy
IV method: The dose is titrated to 10 mg or less before the procedure
The cumulative dose should not exceed 20 mg
The great thing about using diazepam is that it helps in reducing the dose of narcotics by one third
IM method: from 5 to 10 mg 30 minutes before the procedure
Preoperative sedation
10 mg intramuscularly before surgery
Sedation in the ICU
5 to 10 mg intravenously, then 0.03 to 0.1 mg/kg every 30 minutes to 6 hours
Muscle spasms
2 to 10 mg orally 3 to 4 times per day or 5 to 10 mg intravenously or intramuscularly initially, then every 3 to 4 hours if needed
Drug-drug interactions
The FDA (Food and drug administration) has issued a black box warning about the use of diazepam with opioid medications, the concomitant use may result in profound sedation, respiratory depression, coma, and death.
Diazepam may cause serious interactions if used with these drugs, use an alternative
- abametapir
- apalutamide
- benzhydrocodone/acetaminophen
- calcium/magnesium/potassium/sodium oxybates
- carbamazepine
- cimetidine
- clarithromycin
- darunavir
- erythromycin base
- erythromycin ethylsuccinate
- erythromycin lactobionate
- erythromycin stearate
- fedratinib
- fexinidazole
- hydrocodone
- idelalisib
- ivosidenib
- ketoconazole
- lonafarnib
- metoclopramide intranasal
- mifepristone
There is a list of other drugs that need close monitoring when used with diazepam, always tell your doctor about the drugs you are using before letting him prescribing you a new one.
How long is diazepam in your system?
Diazepam is a fast-acting drug.
When it is taken intravenously, it starts to work within 1 to 3 minutes, but if it is taken orally it takes between 15 to 60 minutes to work.
Diazepam is well absorbed about more than 90 % when taken orally.
How long is diazepam in your system?
Diazepam is a long-lasting drug.
It has a half-life of approximately 48 hours; the half-life is the time for half the dose to get from the body.
How long is diazepam in your system?
Metabolites (the substances produced from the breaking down of diazepam in the body) of diazepam can be detected in different ways.
Urine
Diazepam is detected in urine from 1 to 6 weeks.
Blood
Diazepam is detected in blood from 6 to 48 hours.
Saliva
Diazepam is detected in saliva from 1 to 10 days.
Hair
Diazepam is detected in the hair follicle for up to 90 days.
Finally, diazepam is a well-studied drug, which has proved very good effectiveness and a good range of safety.
Always discuss with your doctor the information you read in a medical article.
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