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Home/Pharma information/Warfarin side effects erection

Warfarin side effects erection

Posted by : admin / On : August 21, 2021 / In : Pharma information
Warfarin side effects erection

Table of Contents

  • Warfarin side effects erection
    • What is Warfarin?
    • Warfarin side effects:
    • Contraindications of Warfarin:
    • Warnings and Precautions:
    •  Risk factors of major bleeding with Warfarin:
    • Drug-drug interactions:
    • Drug-Food interaction:
    • Special population:
    • Who should not take Warfarin?
    • What is Erectile Dysfunction?
    • Treatment of Erectile Dysfunction:

Warfarin side effects erection

Warfarin side effects erection:

Many questions about Warfarin side effects erection, Warfarin or other products contain coumadin no evidence can cause Erectile Dysfunction as side effects. All manufacturers do not list Erectile Dysfunction side effects list. So, warfarin side effects erection is not a correct term.

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What is Warfarin?

Warfarin is one of the blood thinner group medications, in another word called anticoagulant medication.

Warfarin is used for preventing blood clots so act for protection from stroke or heart attack. It is also used in the treatment of venous thromboembolism and pulmonary embolism.

Warfarin side effects erection

Warfarin side effects:

  • Major hemorrhage.
  • Vasculitis (is an inflammation of blood vessels).
  • Skin necrosis.
  • Abdominal pain, bloating.
  • Nausea, vomiting.
  • Hypersensitivity reaction.
  • Acute renal failure.

Contraindications of Warfarin:

  • Hypersensitivity to Warfarin.
  • Active gastrointestinal ulcer.
  • CNS hemorrhage.
  • Recent surgery of the eye or CNS.
  • Resistant hypertension.
  • Pericarditis (inflammation of the pericardium).
  • Pericardial effusion.
  • Eclampsia, preeclampsia (a condition of high blood pressure that causes seizure during pregnancy).

Warnings and Precautions:

  1. History of kidney disease: increased risk of acute kidney injury.
  2. Hypersensitivity: use with caution in patients with anaphylactic disorder.
  3. Bleeding: major bleeding is one of the major side effects of using Warfarin.
  4. Skin necrosis or gangrene: this side effect is usually occurred within the first few days of therapy and is frequently localized to the limbs or breast.
  5. Thyroid disease: use with caution in patients with thyroid disease.
  6. Infection: acute infection or active TB disruption of normal gastro-intestinal flora, may alter the response to Warfarin.
  7. Hepatic impairment: increase Warfarin sensitivity.
  8. Dietary insufficiency: use with caution in patients with prolonged dietary insufficiency.
  9. Before surgery: your doctor will confirm you to discontinue for 5 days before surgery.

 Risk factors of major bleeding with Warfarin:

  • Age > 65 years.
  • History of gastrointestinal bleeding.
  • Cerebrovascular disease.
  • Heart disease.
  • Renal impairment.
  • Open wound.
  • Menstruating and postpartum women.
  • Drug-food interaction.
  • Drug-drug interaction, so you should tell your doctor about your medication before starting using Warfarin.

Drug-drug interactions:

If you take one of the following medications, your doctor will advise you to avoid the use of Warfarin:

Another group of medications increases the activity of Warfarin that may induce toxicity:

  • Deoxycholic acid.
  • Also, some medications decrease the activity of Warfarin:
  • Antithyroid agent.
  • Caffeine and caffeine-containing products.
  • Coenzyme Q-10.
  • Cholestyramine resin.
  • Estrogen derivatives.
  • Green tea.

Drug-Food interaction:

Effect of Warfarin decrease by taking certain food like foods rich in vitamin K or drinking alcohol.

Vitamin E, Cranberry juice may increase the Warfarin effect.

Your doctor will advise you to maintain a consistent diet and take Warfarin at the same time each day.

Special population:

  • Geriatric: age over 60 years tend to use lower doses due to decreased metabolism of Warfarin and increase risk of bleeding. Take into consideration all medications you take and tell your doctor to check if their interaction or not.
  • Pediatric: Warfarin can be safely used in infancy to age < 18years with close follow-up and tailored dose.
  • Pregnancy: not advisable to take Warfarin during pregnancy as it crosses the placenta, has a teratogenic effect on fetus and CNS abnormalities. Reported that spontaneous abortion may occur.
  • Lactating women: Warfarin is not present in breast milk, so it is safe to be used by lactating women.

 

Who should not take Warfarin?

There are many conditions considered as contraindicated to take Warfarin, so you need to refer to your doctor if you have one of the following conditions:

  • Cancer or malignancy.
  • Low vitamin k level.
  • Eye operation.
  • A hemorrhage in the brain.
  • Severe liver disease.
  • Severe renal impairment.
  • Recent operation.
  • Major traumatic injury.
  • Operation on the spine.
  • Caloric undernutrition.
  • Decreased platelets due to medications like heparin.
  • Uncontrolled high blood pressure.
  • Stomach or intestinal ulcer.
  • Blockage of a bile duct.
  • Excessive diarrhea.

What is Erectile Dysfunction?

Erectile dysfunction is a problem of getting or keeping an erection firm enough for the risk. It is sometimes called impotence which is a sexual disorder in men.

There are many causes of Erectile Dysfunction:

  • Cardiovascular disorder.
  • Sleep disorder.
  • Old age over 50 years.
  • Multiple sclerosis.
  • Prostate cancer.
  • Renal disorder.
  • Substance abuse.
  • Parkinson’s disorder.
  • Enlarged prostate.
  • High cholesterol level.
  • Certain medications like antidepressants, sleeping pills, some peptic ulcer medications, and blood pressure medications.

Treatment of Erectile Dysfunction:

  • Treatment cause and reverse risk factor.
  • Acupuncture (traditional Chinese treatment).
  • Herbal medicine.
  • Control blood pressure, glucose level.
  • Smoking cessation.
  • Regular exercise.
  • Avoid drug abuse.
  • Relieve your stress.
  • Maintain a healthy diet.
  • Eat a healthy diet.

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