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Home/Archive for: January 2021
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Nowadays erectile dysfunction is a very common case. Viagra is a drug used to treat erectile dysfunction, let’s go through what’s Viagra, what is it used for, and other commonly asked questions.

 

Erectile dysfunction

Erectile dysfunction (ED) is defined as the inability to get and maintain an erection sufficient to have sexual intercourse.

Origin can be medical as the result of a medical condition affecting the blood supply of the penis and/or nerves. It also can be psychological due to stress.

 

Some recreational drugs, smoking, and alcohol can also cause erectile dysfunction.

 

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What is Viagra?

Viagra is the brand name of sildenafil. Sildenafil is used for the treatment of erectile dysfunction. It belongs to a class of drugs called PDE5 inhibitors.

 

How does Viagra work?

PDE5 inhibitors work by inhibiting the degradative action of the PDE5 enzyme (phosphodiesterase type 5), which plays an important role in regulating blood flow to the penis. 

 

Viagra works by increasing blood flow into the spongy-like tissue (the penis). This makes it easier to have and maintain a firm erection. 

 

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What if you drink alcohol while taking Viagra?

It’s heavily advised not to combine alcohol with Viagra. Viagra lowers your blood pressure, as does alcohol, so you may experience unwanted side effects. These include:

 

  • Dizziness
  • Headache
  • Heart palpitations
  • Fainting

 

In another perspective, drinking alcohol has a negative impact on getting an erection. Therefore alcohol directly interferes with the Viagra pharmacological effect. 

 

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How long does Viagra take to work?

Viagra is taken orally and absorbed quickly by the bloodstream.

Usually, it starts to work within half an hour. 

 

It’s preferred to take Viagra on a relatively empty stomach about one hour before having sex as heavy meals may delay its action.

 

How long does the Viagra effect last?

Generally, everyone metabolizes medications differently. However,

Most people will feel the strongest effects of the drug for three to four hours.

 

Small amounts of Viagra could remain in your body for up to 20 hours.

 

What is the recommended dose of Viagra?

Viagra or sildenafil is available in several different doses. Available doses are 25mg, 50 mg, and 100 mg.

Generally, a dose of 50 mg is recommended for men with mild to moderate erectile dysfunction. However, your doctor will advise you with a suitable dose depending on the severity of your erectile dysfunction symptoms. 

 

What can you do to have a good erection other than taking viagra?

  • Eat healthy food.
  • Do some exercise.
  • Quit smoking.
  • Manage your stress.

 

If you’re considering taking Viagra:

  • Talk to your doctor and discuss if it’s suitable for you or not.
  • Tell your doctor about your health condition.
  • Tell your doctor about all the medications you take, including prescription drugs, nonprescription drugs, and herbal medicines.

 

Having good sexual health is a very important issue to maintain a good life, don’t hesitate to consult your family doctor about any problems you have.

 

 

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Nowadays anxiety disorders are very common. Xanax is a drug used to treat anxiety, let’s go through what’s Xanax, what is it used for, and other commonly asked questions.

 

Anxiety disorders

Anxiety is a normal feeling that progresses as a response to stress but when a person regularly feels extreme levels of anxiety that interfere with life, it might become a medical disorder.

Anxiety disorders are categorized as mental health problems that lead to excessive fear, nervousness, and worry.

 

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What is Xanax?

Xanax is the brand of Alprazolam. Alprazolam is used for the treatment of anxiety, anxiety caused by depression, and panic disorders. It belongs to a category of medications called benzodiazepines which act on the central nervous system to produce a sedating effect. It works by enhancing the effects of a certain neurotransmitter in the body (GABA).

 

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Does it feel the same for everyone?

Xanax, or its generic version of alprazolam, doesn’t affect everyone in the same way.

 

How Xanax will affect you depends on some factors, including:

 

  • Mental status 
  • Dose
  • Age
  • Weight
  • Metabolism

 

If you’re taking Alprazolam for the first time, it’s important to know more about its side effects and interactions before use. 

We will explain to you what it should feel like.

 

What does Xanax feel like if you’re using it while it’s not prescribed to you?

Many people who take Xanax without a prescription, say that it has a sedating or calming effect. They say that they feel quiet and tired unlike some drugs, such as cocaine, that produce a euphoric feeling.

 

Some people have also reported memory loss, feeling to pass out, or blacking out.

 

What if you’re using it for the treatment of anxiety or panic disorder?

If you take this medication as prescribed for anxiety or panic disorders you may feel normal after your first dose.

 

The sedating effect can help calm you down and reduce anxiety and stress.

 

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What if you drink alcohol after taking Xanax?

Alcohol slows down Xanax clearance from your body so it increases the effects of this medication. If you take Xanax and then drink alcohol, you may experience extreme drowsiness and prolonged memory loss.

 

It’s heavily advised not to combine alcohol with Xanax, it’s a very dangerous combination that causes serious side effects. These include:

 

  • Dyspnea
  • Lethargy
  • Confusion
  • Seizures

 

How long does Xanax take to work?

Xanax is taken orally and absorbed quickly by the bloodstream.

Usually, it starts to work within an hour. However, some people may feel the effects of Xanax within 5 to 10 minutes of taking the tablet.

 

This quick effect makes Xanax very effective for treating panic.

 

How long do Xanax effects last?

Generally, everyone metabolizes medications differently. However,

Most people will feel the strongest effects of the drug for two to four hours.

How long it takes Xanax to give an impact on you will depend on several factors. They include:

 

Weight 

Metabolism

Age

Other medications patient may be taking

 

If you’re considering taking Xanax, please talk to your doctor and discuss if it’s suitable for you or not.

 

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Valium is a very potent and effective drug but has a lot of safety issues which you should know before starting to use it.

 

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Special Alerts about benzodiazepines use

The FDA (Food and Drug Administration) announces that it is requiring an update to benzodiazepine products’ Boxed Warning to include the risks of misuse, addiction, abuse, withdrawal reactions, and physical dependence to improve their safe use. The FDA is also requiring other changes to the Warnings and Precautions, Drug Abuse and Dependence, and Patient Counseling Information sections of the prescribing information for all benzodiazepine products. 

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Risks from concomitant use with opioids:

Concomitant use of benzodiazepines and opioids may result in respiratory depression, profound sedation, coma, and death. Reserve concomitant prescribing only if no alternatives are available. Limit dosages and durations to the minimum required. Follow up on the signs and symptoms of respiratory depression and sedation.

Abuse, misuse, and addiction:

The use of benzodiazepines, including Valium, exposes users to risks of misuse, abuse, and addiction, which can lead to overdose or death. Abuse and misuse of benzodiazepines commonly involve concomitant use of other medications, alcohol, and/or illicit substances, which is associated with an increased frequency of serious adverse outcomes. Before prescribing Valium and throughout treatment, assess each patient’s risk for abuse, misuse, and addiction.

Dependence and withdrawal reactions:

The continued use of benzodiazepines, including Valium, for several days to weeks can result in significant physical dependence. sudden discontinuation or rapid dosage reduction of Valium after continued use may cause acute withdrawal reactions, which can be life-threatening. To reduce this risk, use a gradual taper to discontinue Valium or reduce the dosage.

Adverse Reactions

Incidence higher than 10%: Nervous system: Drowsiness (23%)

Incidence from 1% to 10%:

  • Cardiovascular: Hypotension (1% to 2%), vasodilation (1% to 2%)
  • Dermatologic: Skin rash (3%)
  • Gastrointestinal: diarrhea (4%) ,abdominal pain (≥1%), dysgeusia (2%)
  • Nervous system: emotional lability (≥1%), agitation (≥1%), headache (5%), confusion (≥1%), dizziness (3%), abnormality in thinking (1% to 2%) , euphoria (3%),  nervousness (≥1%), speech disturbance (≥1%), pain (≥1%).
  • Neuromuscular & skeletal:  lack of energy and strength (1% to 2%)
  • Respiratory: Asthma (2%), bleeding per nose (3%), nasal congestion (3%), nasal discomfort (6%), inflammation and swelling of the mucous membrane of the nose (≥1%)
Incidence less than 1%:
  • Cardiovascular: decrease in heartbeats, syncope.
  • Dermatologic: increase sweating of skin, pruritus, urticaria.
  • Gastrointestinal: anorexia, vomiting.
  • Genitourinary: urinary tract infection
  • Hematologic & oncologic: anemia, decrease in white blood cell count.
  • Infection: Infection.
  • Nervous system: convulsions.
  • Neuromuscular & skeletal: hyper muscle activity.
  • Respiratory: cough.
Frequency not defined:
  • Endocrine & metabolic: Change in libido
  • Gastrointestinal: altered salivation, constipation, gastrointestinal distress, hiccups, nausea
  • Genitourinary: urinary incontinence, urinary retention
  • Hematologic & oncologic: neutropenia
  • Hepatic: increase in liver function tests.
  • Nervous system: drug dependence, central nervous system depression, depression, anterograde amnesia,  drug withdrawal, dysarthria, fatigue, hypoactivity, paradoxical central nervous system stimulation, psychiatric signs and symptoms, vertigo, slurred speech
  • Neuromuscular & skeletal: Tremor
  • Ophthalmic: Blurred vision, diplopia
Contraindications
  • untreated open-angle glaucoma.
  • infants <6 months of age.
  • myasthenia gravis.
  • severe respiratory impairment.
  • severe hepatic impairment.
  • sleep apnea syndrome.

        Pregnancy Considerations

Valium crosses the placenta. Teratogenic effects have been observed with Valium; however, more studies are needed. The incidence of low birth and premature birth weights may be increased following maternal use of Valium.

Hypoglycemia and respiratory problems are common with the neonate following exposure late in pregnancy. Neonatal withdrawal symptoms may occur within days to weeks after birth. Monotherapy with the lowest dose should be considered in women with epilepsy. Avoidance of medications with a high incidence of teratogenic effects is recommended.

Breast-Feeding Considerations

Valium and its metabolites are present in breast milk.

Sedation and weight loss have been observed in some infants exposed to Valium via breast milk. 

Valium has a long half-life and may accumulate in the breastfed infant, especially preterm infants or those exposed to chronic maternal doses. Significant accumulation may occur even if the maternal dose is low. A single maternal dose may be compatible with breastfeeding. 

 

 

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In fact, these tablets may cause many problems for many people, especially when taking before consulting a doctor about the possibility of taking Imovane, as these pills may cause addiction in the case of randomly increasing daily doses, or taking some people such as the elderly, children or young people younger than 18 years old.

Although these tablets treat many mental illnesses such as insomnia, fatigue, and the inability to sleep normally and continuously, especially in the evening after finishing school or workday.

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One of the most common questions that many seek an answer to on websites, especially in the United Kingdom.

Where many try to take these pills without consulting a doctor, in order to help them sleep continuously, comfort their nerves, and get rid of daily stress, whether at work or study.

Patients will not be able to take Zopiclone pills without consulting a doctor, as taking these tablets may cause several diseases and major problems, especially in the case of abuse by people who are not permitted to use Zopiclone at all, such as the elderly, infants, children, people under 18 years of age or patients with mental illness. Or people who take other medicines to treat depression.

 

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People and patients who took zopiclone pills assured that they can sleep in the evening for hours at a time and get rid of anxiety and fatigue.

These tablets can be taken one hour before bed, as they are very effective and may cause sudden falls and loss of consciousness for many people, especially the elderly.

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In this article we will review some important information you should know about this medication, what it’s used for, and how it’s used, Let’s go through.

 

 

What is diazepam?

Diazepam oral tablet is a drug that’s available as the brand name Valium and also available as a generic drug with lower cost.

Diazepam is also available as a liquid nasal spray, an oral solution, and an intravenous injection.

 

What is it used for?

Diazepam oral tablet is indicated for the following conditions:

 

Anxiety

agitation or tremors caused by alcohol withdrawal

Adjuvant therapy for skeletal muscle spasms

Adjuvant therapy for certain types of seizure

 

Adjuvant therapy means that It may be used as part of combination therapy, you still need to take it with other drugs.

 

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How does it work?

Diazepam belongs to a class of drugs called benzodiazepines (a group of drugs that has a similar chemical structure, attaches to the same receptors so works similarly, and is often used to treat similar conditions).

 

Diazepam increases the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that can send signals throughout your nervous system. If you don’t have enough GABA, your body may have anxiety and you may have difficulty falling asleep.

By taking diazepam, GABA will be increased in your body. This will help decrease your restlessness spasms, and/or seizures.

 

What are the common side effects if you buy diazepam 10mg?

Diazepam can cause mild or severe side effects, but we will go through the common side effects:

 

Headache

Nausea

Dizziness

Drowsiness

Tremor

Spinning sensation,

Tired feeling or fatigue

Muscle weakness 

Inability to control muscle movements 

Memory problems

Dry mouth or excessive saliva

Constipation

 

For more information on the possible side effects of diazepam and if you developed any unusual symptoms, talk with your doctor or pharmacist.

 

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Before starting and during diazepam use, your doctor will put you on monitoring

 

Liver function: Liver function tests are done to help your doctor decide if diazepam is safe for you and if you need a special dose adjustment.

 

Kidney function: Kidney function tests are done to help your doctor decide if diazepam is safe for you and if you need a special dose adjustment.

 

Breathing rate: Your doctor will monitor your breathing rate during treatment as diazepam could make your breathing rate too low.

 

Mental status: Your doctor will monitor you during treatment as diazepam could cause changes in thinking or memory.

 

IMPORTANT INFORMATION

  • Don’t drink alcohol while taking diazepam, this combination can cause serious side effects. Problems with thinking, judgment and motor skills could happen. It can make you drowsy and cause your breathing to slow down or stop.

Also, your body processes alcohol and this drug in similar bath ways, so if you drink alcohol, diazepam could take longer to get out of your body. This may worsen your side effects.

 

  • Don’t use opioid drugs while taking diazepam, this can cause serious side effects. These can include severe drowsiness, slowed breathing, coma, and death. 

 

  • Diazepam may interact with other medications, tell your doctor about any drug you use including prescription drugs and nonprescription drugs, and herbal medicines.
  • Don’t begin using new drugs without your doctor’s prescription.

 

Generally

The information contained here is not absolute, inclusive, or totally complete. 

It doesn’t cover all possible uses, precautions, drug or food interactions or side is a prescription drug, we don’t admit this drug is safe or effective for you or it’s not.

Ask your healthcare provider about any information you need to know.

 

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What is Viagra?

  • Viagra tablets contain a drug called sildenafil. Sildenafil is used for erectile dysfunction in men.
  • Viagra works by increasing blood flow to the penis, besides sexual stimulation, which allows erection and maintenance of it.

 

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NOTE

  • The information here is given to help you understand more about this drug. The information is not totally inclusive. It’s not intended to cover all possible indications, dosing, precautions, interactions, or side effects.
  • Viagra is a prescription drug, we don’t admit it’s safe for you or for anyone.
  • Ask your healthcare provider before use.
  • Follow your doctor’s instructions strictly for your goodness.

 

How to use Viagra?

  •  Viagra is a prescription drug, take it exactly as your doctor tells you. He will tell you how much viagra to take and how.
  • Viagra has no role with sexual arousal, Get into the mood. You cannot get an erection without physical or emotional sexual stimulation, taking Viagra only is not enough.
  •  Viagra should be taken within 30-60 minutes before sexual activity. It is still working up to 5 hours from intake.
  • Don’t eat a heavy meal, Viagra can be taken with or without food but If you take Viagra after a heavy meal, it could take more time to start working.
  •  Viagra couldn’t be taken more than once daily.
  •  If you take too much Viagra by accident, call your doctor or seek a medical emergency right away.

 

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IMPORTANT INFORMATION 

  • Viagra is your drug, never pass it to others, follow your doctor’s instructions about it.
  • Take the tablet with plenty of water.
  • Viagra can be taken with or without food but avoid taking it after a fatty meal, this can delay its action.
  • Never take more than one tablet per day.

 

Before taking Viagra

1- Read the instructions of the package leaflet carefully.

 

2- Viagra can cause sudden blood pressure-lowering if you are taking another blood pressure-lowering drug, that could be life-threatening. Do not take Viagra if you take any other medicines containing nitrates. Nitrates are used to treat angina. If this happened you could feel dizzy, faint, or have a stroke or heart attack.

 

3- Do not take Viagra if you are using Riociguat (Adempas®), a medicine that treats chronic-thromboembolic pulmonary hypertension and pulmonary arterial hypertension.

 

4- Tell all your healthcare providers that you are using Viagra so If you need emergency medical care for a heart problem, it will be serious for your healthcare provider to know that you are using Viagra and when did you take it last time.

 

5- If you had symptoms such as dizziness, chest pain, or nausea during sex, seek medical help immediately.

 

6- If you already have heart problems, sexual activity could put your heart under extra stress. Ask your doctor if your heart is healthy enough to deal with the extra stress of having sex.

 

7- Inform your doctor if you have any of the following conditions:

  • Kidney dysfunction
  • Liver dysfunction
  • Stroke
  • Heart surgery within the last 6 months
  • Chest pain or aortic valve narrowing
  • Recent heart attacks
  • Angina
  • Uncontrolled blood pressure
  • Heart failure.
  • Chronic pulmonary disease
  • Pulmonary hypertension
  • Penis deformity 
  • Bleeding tendency and/or problems with your blood cells

 

Tell your doctor thoroughly about your health condition and about every drug you use including prescription drugs, nonprescription drugs, and herbal remedies.

 

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Warnings/Precautions

Issues related to adverse effects if you buy sildenafil 100mg UK :

Hearing loss: some reports of Sudden decrease or loss of hearing. tinnitus and dizziness may be accompanied by hearing changes. No direct relationship between sildenafil and hearing loss has not been determined.

Color discrimination: impairment of color discrimination which is dose-related, Use with caution in case of retinitis pigmentosa.

Decrease in blood pressure (hypotension): those on antihypertensive therapy or fluid depletion may be more sensitive to hypotensive actions. measure blood pressure prior to initiating therapy (start the lowest possible dose). Ethanol may increase the risk of hypotension and orthostasis, avoid or limit ethanol consumption.

Priapism: Painful erection >6 hours has been reported rarely, seek medical assistance for an erection lasting >4 hours.

Vision loss: reports of Sudden loss of vision in one or both eyes, including permanent loss of vision. Other risk factors include smoking, coronary artery disease, diabetes, hyperlipidemia, hypertension, and >50 years of age.  discontinue therapy if you are suffering sudden vision loss and consult a health care provider immediately. No direct relationship between therapy and vision loss has not been determined.

Disease-related issues:

 Use caution in patients with anatomical deformation of the penis.

Use with caution in case of bleeding disorders; safety has not been established.

Use with caution in case of hypotension (<90/50 mm Hg); uncontrolled hypertension (>170/110 mm Hg); irregular heartbeats,  MI or stroke within the last 6 months; coronary artery disease causing unstable angina or cardiac failure; safety and efficacy have not been studied in these patients. 

Use with caution in case of conditions that may predispose them to priapism (sickle cell anemia, multiple myeloma, leukemia). seek immediate medical attention if the erection persists >4 hours.

Hepatic impairment: use the lowest starting dose (25 mg) of Viagra.

safety has not been established, Use with caution in case of active peptic ulcer disease.

Pulmonary arterial hypertension:  an exacerbation of pulmonary arterial hypertension (PAH) can occur after sudden cessation of sildenafil monotherapy, safety of longer-term use is unclear. 

Renal impairment: dose adjustment may be needed, use the lowest starting dose (25 mg) in severe dysfunction (CrCl <30 mL/minute).

Sickle cell anemia: The effectiveness and safety of sildenafil have not been established in pulmonary hypertension secondary to sickle cell disease. Use with caution

Food Interactions if you take sildenafil 100mg UK

serum levels/toxicity of orally administered sildenafil can be increased with Grapefruit juice, Monitor for increased effects/toxicity with concomitant oral use.

sildenafil 100mg UK

sildenafil 100mg UK

Contraindications

Concurrent use with certain drugs such as:

Any drug contains organic nitrates in any form (eg, nitroglycerin, isosorbide dinitrate).

Riociguat drug.

protease inhibitors (tipranavir, atazanavir, nelfinavir, indinavir,darunavir, fosamprenavir, lopinavir/ritonavir, ritonavir, saquinavir, )

Pregnancy Considerations

Sildenafil was shown to cross the placenta, due to adverse events in the newborn observed using preliminary data from a study evaluating sildenafil for fetal growth restriction, use of sildenafil in pregnant women outside of a controlled clinical study is not currently recommended. Information related to the use of sildenafil for the treatment of pulmonary arterial hypertension (PAH) in pregnant women is limited. Untreated PAH in pregnancy increases the risk of heart failure, stroke, preterm delivery, and maternal/fetal death. Women with PAH are encouraged to avoid pregnancy. 

Breast-Feeding Considerations

Sildenafil is excreted in breast milk.

The excretion of sildenafil in breast milk was described in a case report following maternal use for the treatment of PAH.

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Before ordering the purchase of Zopiclone pills, you must consult your doctor, as the appropriate dose is determined, and many people may suffer from some side effects when taking the tablets.

Also, some people cannot take zopiclone, such as the elderly, infants, or pregnant women.
Also, people who take other medicines to treat epilepsy or mental illnesses can not take these pills.

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Consult a doctor about zopiclone pills and can you take them without experiencing problems or side effects?

Imovane will help you get relief, these pills have helped many people sleep normally and get rid of insomnia problems.

The doctor sets a time for the patient to stop taking these tablets so that he is not exposed to problems such as addiction.
Also, patients must adhere to the dose prescribed by the doctor and take it on time.

we will show you when to take a zopiclone dose. Many people wonder when is the best time to take zopiclone?

The best time is one hour before going to sleep, as the effect of these tablets is strong, which causes rapid sleep.

Therefore, it is not recommended to take these tablets while driving or doing important work, as the person may experience fainting or loss of consciousness.

People who drink alcohol cannot use these tablets as they can cause major problems. You should also stop taking any other medications to treat insomnia while using these tablets.

 

 

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