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Home/Pharma information/Pregabalin for pain

Pregabalin for pain

Posted by : admin / On : May 28, 2021 / In : Pharma information
pregabalin for pain

Table of Contents

  • Pregabalin for pain
    • What is Pregabalin for pain?
    • How does Pregabalin for pain work?
      • Regular-release capsules
      • In the management of postherpetic neuralgia:
      • In the management of fibromyalgia (a condition that is characterized by pain as the main symptom of it):
        • Warnings:

Pregabalin for pain

Pain, this sensation that ranges from just an annoying feeling to a debilitating feeling that can impede the life of the patient.

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Two kinds of pain are specifically very irritating, Neuropathy and Neuralgia.

Neuropathy is pain, numbness, tingling, swelling, or muscle weakness in different parts of the body, it usually occurs in the hands or feet, and worsens with time.

Neuralgia happens as a result of damage or irritation to the nerve which causes pain along the nerve pathway.

This pain is illustrated as burning, stabbing, sharp or shocking pain.

And we have the drug for both kinds of pain, and other kinds of pain also, Pregabalin for pain.

What is Pregabalin for pain?

Pregabalin got approval from the United States FDA (Food and Drug Administration) for the management of neuropathic pain caused by diabetes, spinal cord injury, and postherpetic neuralgia.

It is also got approval for the management of pain caused by fibromyalgia.

Pregabalin is used for chronic pain conditions not approved by FDA.

Pregabalin is not just for pain, it is also used as adjunctive therapy for partial-onset seizures.

Off-label uses like generalized anxiety disorder, social anxiety disorder, bipolar disorder, and insomnia.

 

How does Pregabalin for pain work?

Pregabalin for pain controls the chemicals which send the pain signals to nerves, to reduce how much you feel the pain you suffer from.

Dosage and administration:

Pregabalin for pain is found in many dosage forms and concentrations.

Capsules, extended-release tablets, and oral solutions.

It is not found as injectable forms.

In the management of peripheral neuropathic pain caused by diabetes:

Regular-release capsules

  • Start the dose by 50 mg orally every 8 hours.
  • It may be increased to 100 mg orally every 8 hours within 1 week according to the medical condition.
  • Maximum dose: The dose should not exceed 300 mg per day.

 

pregabalin for pain

pregabalin for pain

Extended-release tablets

  • Start the dose by 165 mg orally every 24 hours.
  • It may be increased to 330 mg orally every 24 hours within 1 week according to the medical condition.
  • Maximum dose: The dose should not exceed 330 mg per day.

In the management of postherpetic neuralgia:

Regular-release capsules

  • Start the dose by 150-300 mg orally every 8-12 hours.
  • It may be increased to 300 mg orally every 8-12 hours within 1 week according to the medical condition.

Extended-release tablets

  • Start the dose by 165 mg orally every 24 hours.
  • It may be increased to 330 mg orally every 24 hours within 1 week according to the medical condition.
  • Maximum dose: 330 mg orally per day.

After 2-4 weeks, the patient may develop tolerance to the dose, so according to the doctor’s advice, the dose may be increased to 660 mg orally per day.

In the management of fibromyalgia (a condition that is characterized by pain as the main symptom of it):

Regular-release capsules and oral solutions are the only forms used for the management of fibromyalgia.

  • Start the dose by 75 mg orally every 12 hours.
  • It may be increased to 150 mg every 12 hours within 1 week according to the medical condition.
  • Doses more than 450 mg per day are not recommended.

In the management of neuropathic pain caused by spinal cord injury:

Regular-release capsules and oral solutions are the only forms used for the management of neuropathic pain caused by spinal cord injury.

  • Start the dose by 75 mg orally every 12 hours.
  • It may be increased to 150 mg every 12 hours within 1 week according to the medical condition.

After 2-3 weeks, tolerance to the dose may occur; the doctor may advise increasing the dose to 600 mg per day.

  • For patients suffering from any form of renal impairment, the doctor will change the dose according to the condition of the patient.
Warnings:
  • Patients who suffer from hypersensitivity to Pregabalin for pain cannot take this drug at all.
  • If you suffer from any kind of hypersensitivity, you must tell your doctor before taking pregabalin for pain.
  • If you are taking thiazolidinedione antidiabetic drugs, peripheral edema and weight gain are highly susceptible to occur.
  • Before consuming Pregabalin for pain, you must understand how you will react to the dizziness and somnolence caused by it before driving or performing any hazardous activities.

This may cause dangerous accidents.

  • Symptoms like insomnia, nausea, headache, anxiety and diarrhea were stated after the sudden stop of Pregabalin for pain, even increased seizures with patients with seizures disorder.

Pregabalin for pain should not be stopped suddenly; it should be decreased gradually to avoid withdrawal symptoms.

Pregabalin for pain is potent, very effective, and fewer side effects causing drugs.

Consult with your doctor about the benefits and harms of Pregabalin for pain, and how effective it will be for your condition.

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