Zopiclone and Diazepam
Table of Contents
Zopiclone and Diazepam
What is Zopiclone and what it is used for?
Zopiclone belongs to a group of medicines called hypnotics (sleeping pills).
They are used for short term treatment of insomnia (sleep problems) for patients above 18 years old suffering from:
- Difficulty in falling asleep.
- Waking up at night or early in the morning.
- Sleep problems that caused by mood or mental health problems.
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Don’t take Zopiclone if you:
- Have myasthenia gravis (a problem that causes severe muscle weakness).
- Have Respiratory problems (lungs don’t work properly).
- Have sleep apnea (stop breathing at night).
- Have hepatic problems.
- Have renal problems.
- Are Less than 18 years old.
- Have a history of alcohol or drug abuse.
Zopiclone is not to be used as a long-term treatment due to the risk of dependence, always consult your doctor for the proper duration of using it.
Zopiclone and Diazepam
Common side effects of Zopiclone:
Like all drugs Zopiclone may cause serious side effects, you should tell your doctor as soon as possible if you suffer one or more of the following side effects:
- Amnesia (total or partial memory loss).
- Hallucinations (seeing or hearing things that are not real).
- Delusions (thinking things that are not real).
- Dry mouth.
- Metallic taste in your mouth.
- Feeling sleepy.
- Nausea and vomiting.
- Itchy rash.
- Reduced sex drive.
What is Diazepam and what it is used for?
Diazepam belongs to a group of medicines called benzodiazepines which are used mainly in the treatment of anxiety, muscle spasm, and convulsions.
- In adults, Diazepam is used as a short-term treatment of anxiety, muscle spasm, alcohol withdrawal, and epilepsy (together with other drugs).
- In children, Diazepam is used to treat tension caused by cerebral spasticity (disease or trauma affecting the brain causing un-coordinated movement and stiffness).
Common side effects of Diazepam:
- Respiratory depression or arrest.
- Ataxia (movement disorders).
- Swelling and skin rash.
What are drug interactions?
Taking more than one medication, or mixing it with certain foods, or over-the-counter medicines makes you subjected to the risk of a drug interaction. Although most of these interactions are not serious, it is important to know the possible outcome of these interactions.
The most famous drug interaction is the drug-drug interaction, where one drug may increase or decrease the work of the other one leading to toxicity or decreasing the medication effect.
Zopiclone (non-benzodiazepine hypnotic) and Diazepam (benzodiazepine) are both prescribed for the treatment of insomnia (sleeping disturbance), however, Zopiclone is much effective as a hypnotic than Diazepam, as Diazepam is mainly prescribed as an anti-anxiety drug.
One of the most famous drug-drug interactions is the use of Zopiclone and Diazepam together.
Zopiclone and Diazepam are contraindicated drugs both have CNS depressant effects, Zopiclone exerts its action by binding on the benzodiazepine receptor.
Taking Zopiclone and Diazepam together leads to an increase in the risk of severity of the side effects of both of them.
Both Zopiclone and Diazepam have common side effects as:
- Respiratory depression.
- Muscle weakness.
- Allergic reactions (swelling of lips, tongue, and throat, skin rash, and difficulty in breathing).
- Ataxia (loss of coordination of muscle movement).
- Difficulty in breathing.
- Delusions and hallucinations.
Zopiclone and Diazepam are not to be used in the following cases:
- Alcoholism or drug abuse.
- Kidney, liver, or heart failure.
- Epilepsy or history of seizures.
- Sleep apnea (stop breathing for short periods at night).
- Driving and operating machines.
Drugs should not be used with both Zopiclone and Diazepam:
- Medicines for depression (anti-depressants).
- Anesthetics (medicines used in surgery).
- Hypnotics (medicines to relieve anxiety or for sleeping problems).
- Sedative antihistamines (medicines for hay fever and rashes).
- Some antibiotics (as erythromycin).
- Medicines for epilepsy (anticonvulsants as phenobarbital).
- Strong pain killers (as morphine and codeine).
The effect of using Zopiclone and Diazepam during pregnancy:
The use of Zopiclone and Diazepam is not recommended during pregnancy:
- Using during the second or third trimester of pregnancy causes a decrease in fetal movement and fetal heart rate.
- Using at end of pregnancy or during labor, the baby may suffer from breathing problems, muscle weakness, and difficulty in feeding.
- Using regularly at the end of pregnancy, the baby may develop physical dependence and may be at risk of withdrawal symptoms.
The use of Zopiclone and Diazepam is not recommended during lactation:
Both drugs may pass in the mother’s milk and the drug may accumulate in breastfeeding infants, especially with repeated doses.
Consult your doctor to decide to discontinue breastfeeding or discontinuing the drug.
The effects of Zopiclone and Diazepam on the ability to drive and use machines:
Both drugs act by an effect on your central nervous system (slowing the normal brain function), so they may affect the ability to drive or use machines if:
- Taken within 12 hours of performing mental activities that require alertness.
- Taken in a dose higher than the recommended dose.
- Taken with alcohol or with other central nervous system depressants.
For your safety, don’t engage in hazardous activities that require complete mental alertness, taking into consideration commitment to the dose prescribed by your doctor.
Can you take diazepam with naproxen
Table of Contents
Can you take diazepam with naproxen?
What is diazepam and what is naproxen, we have to know first to be able to answer the question can you take diazepam with naproxen?
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Diazepam is a drug belonging to this family affecting the brain producing a calming effect called Benzodiazepines.
It is used to treat anxiety, alcohol withdrawal, muscle spasms, and seizures.
Diazepam is also prescribed for inducing sedation before medical procedures putting the patient on mechanical ventilation, having surgery, or undergoing a dental procedure.
Before taking diazepam, you have to read the medication guide provided with the drug carefully, to avoid any dangers resulting from the misuse of the drug.
If you have any inquiries or any information that is not fully understood, talk to your health care provider about them.
The dose of diazepam is based on many factors, including medical condition, age, and weight of the patient.
Underlying medical conditions are also a factor to be considered when determining the dose.
Take diazepam exactly as prescribed by your doctor, don’t alter the dose, and don’t take it for a longer duration.
If you are going to take the oral solution form, take it with a special measuring device or measuring syringe, don’t take it with the spoons used at home as it may cause incorrect dose.
Diazepam is a drug to be used for a short period, not longer than 4 months unless the doctor decided to elongate the duration of the treatment.
If you miss the dose and didn’t take it at the time required, take it as soon as you remember, but if it is the time for the next dose, skip this dose as doubling the dose may cause an overdose.
Overdose symptoms
Overdose symptoms of diazepam such as extreme drowsiness, inability to keep balanced and to keep good coordination, weakness of muscles, shallow breathing, and coma.
Opioids, a class of drugs used for relieving pain, including illegal drugs like heroin, and legal drugs like oxycodone, using this class with diazepam may cause serious and dangerous problems, including shallow and slow breathing, and also sleeping with difficulty to wake up.
Diazepam can cause a serious allergic reaction, including hives, difficulty in breathing, swelling of the face, lips, tongue, and throat, if you suffer from any of these signs, contact your doctor immediately.
Can you take diazepam with naproxen?
First, we have to be introduced to naproxen.
Naproxen is a drug belonging to a very famous family called NSAIDs (Non-steroidal anti-inflammatory drugs), they reduce the hormones responsible for causing inflammation and pain.
It is used in pain and inflammation caused by arthritis (a disease or pain in joints, one or more), ankylosing spondylitis (a type of arthritis affecting the spine), tendinitis (inflammation of a tendon), bursitis (inflammation in the small filled sacs that cushion the bones, tendons, and muscles near joints, causing pain), gout (intense pain, swelling, and stiffness in a joint which is usually the big toe), and menstrual cramps.
Naproxen also can be used for pain caused by other conditions.
The extended-release tablets and the delayed-release tablets are not suitable for treating acute pain conditions.
Naproxen should not be taken with patients suffering from allergies to it or other NSAIDs.
Using naproxen with high doses and for a long duration increases the risk of fatal heart attack and stroke.
Also, patients with heart diseases may suffer from stroke or heart attack.
Naproxen may cause several dangerous side effects, swelling of the face and throat, chest pain, weakness, shallow breathing, slurred speech, balance, and vision problems, if you suffer from any of these problems, get emergency medical help.
Stop the medication and consult with your doctor immediately if you suffered from stomach pain, tiredness, yellowing of skin and eyes, nausea, vomiting, bloody or black and sticky stools, rash, weight changes, and swelling of hands and feet.
Naproxen or other drugs are used in the least effective dose to avoid undesirable side effects.
One factor which is very important in determining the dosage is weight especially in children, so if you notice any changes in the weight of your child, make sure to inform the doctor to make dose alterations based on the new weight.
Using any drug for a long time needs frequent medical tests to assure that the drug is not affecting the body systems.
Can you take diazepam with naproxen?
If you are going to take for low back pain, studies have shown no benefit of using diazepam over the use of placebo, so don’t add diazepam in combination with naproxen for the management of low back pain.
Can you take diazepam with naproxen?
If you need to potentiate the anticonvulsant effect of diazepam, naproxen is a good choice for doing that.
Can you take diazepam with naproxen?
Yes, no interactions were found between both of them, but of course, individual differences may happen, always tell your doctor about unusual effects happening after taking any drugs.
Ensure the information of any medical article with your health care provider before taking an action according to this information.
Buy Diazepam 2mg online UK
Table of Contents
Buy Diazepam 2mg online UK:
Each tablet contains 2mg of diazepam.
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Indications:
Diazepam 2mg is used for short-term treatment of anxiety including severe anxiety, anxiety that causes unacceptable distress, and anxiety associated with insomnia.
Diazepam is also indicated for symptomatic treatment of acute alcohol withdrawal such as agitation or tremors.
Diazepam is used as an adjunct therapy for certain types of epilepsy.
Diazepam is used as a premed before surgery or for dental operations.
Buy Diazepam 2mg online UK, but your treatment should not exceed 4 weeks and Diazepam should be stopped gradually. An extended withdrawal period may be required for a patient using diazepam for a long time.
What is Diazepam 2mg?
Diazepam is a prescription medicine that belongs to a group of medications called benzodiazepines. Benzodiazepines are antianxiety agents, anticonvulsants, and skeletal muscle relaxants.
Buy Diazepam 2mg online UK, but not for children younger than 6 months of age.
Benzodiazepines have a similar chemical structure and are used to treat similar medical conditions.
Benzodiazepines increase the activity of GABA (gamma-aminobutyric aid) which is a chemical substance that sends signals across the CNS (central nervous system). The decrease of GABA in the brain causes the body to be in an exciting status leading to anxiety, muscle spasms, or seizures.
Dosage:
Diazepam dosage is determined for each individual depending on several factors:
1- Type and severity of the condition
2- Your age
3- Your medical history
For adults:
- For management of anxiety: Diazepam 2mg tablet 2 to 4 times per day.
- For acute alcohol withdrawal: 10 mg 3 to 4 times during the first 24 hours, then reduced to 5 mg 3 or 4 times per day.
- As an adjunctive for relief of skeletal muscle spasm: 2mg to 10 mg 3 or 4 times per day.
- As an adjunctive in convulsive disorders: 2mg to 10 mg 2 to 4 times per day.
For geriatric patients: 2mg 1 to 2 times per day, the dose may be increased gradually as needed.
Drug interactions:
Some medicines are contraindicated together due to their interaction that may cause harmful effects, however, in some cases using these medicines together may be required. In this case, the doctor may change the dose or recommend some precautions to be taken while using these medicines.
The following drugs are not recommended to be used with Diazepam, but if required for certain cases, your doctor should prescribe the suitable dose and determine how often you use one or both the medicines. For example:
- Alprazolam
- Amobarbital
- Alfentanil
- Bromazepam
- Butabarbital
- Calcifediol
- Calcium Oxybate
- Cannabidiol
- Chlorzoxazone
- Difenoxin
- Doxylamine
- Ethylmorphine
- Fentanyl
- Gabapentin
- Hydrocodone
- Metaxalone
- Methadone
- Opium
- Phenytoin
- Propofol
- Tramadol
- Zolpidem
Side Effects:
Buy Diazepam 2mg online UK but you should know first that Diazepam causes side effects that may be mild or severe in some cases. These side effects include:
- Impairment of judgment or thinking as Diazepam slows down your brain’s activity.
- Interference with motor skills.
- Drowsiness
- Tiredness
- Fatigue
- Muscle weakness
- Headache
- Tremors
- Constipation
- Nausea
- Dry mouth
- Excessive saliva
- Ataxia (loss of control of muscle movement)
- Loss of coordination
If these symptoms are severe, call your healthcare provider or ask for immediate emergency attention. If they are mild, they may disappear within a few days or weeks.
Serious side effects like:
- Severe drowsiness
- Depression
- Suicidal thoughts
- Confusion
- Anxiety
- Hallucinations
- Panic attacks
- Hyperactivity
- Agitation
- Aggression
- Sleeping problems
- Hostility
- Worsening seizures
Contraindications:
Diazepam is contraindicated for patients with:
- Hypersensitivity to the active substance
- Acute pulmonary insufficiency
- Myasthenia gravis
- Chronic psychosis
- Sleep apnea
- Severe hepatic insufficiency
- Patients planning a pregnancy
- Pregnant women
Special warnings and precautions for use:
- Avoid using Diazepam for more than 4 weeks.
- Avoid using Diazepam with opioid drugs (like codeine, tramadol, hydrocodone), this may lead to dangerous side effects such as slowed breathing, severe drowsiness, coma, or death.
- Use this drug exactly as prescribed by your healthcare provider. Talk to your doctor if you have any questions about how safely taking this drug.
- Stopping this drug suddenly may lead to physical dependence or severe withdrawal symptoms which can be life-threatening.
- Taking Diazepam may lead to misuse and addiction.
- Avoid driving, operating machines, or other tasks that require alertness.
- This drug may cause more frequent seizures if taken as an adjunct therapy for treating seizures.
- Avoid drinking grapefruit juice while using Diazepam.
- You must tell your doctor if you have kidney problems to avoid the accumulation of Diazepam, as its elimination from your body occurs by the kidneys, this increases the risk of side effects.
- Avoid taking Diazepam while pregnant. Risks of side effects to the fetus may occur. You should weigh the benefits of taking Diazepam against the risks that may occur.
- Diazepam passes into the breast milk and can cause serious side effects, so if you are breastfeeding talk to your doctor before taking Diazepam.
- Be sure that this drug is out of reach of children.
- Store Diazepam at room temperature 59-86◦ F (15-30◦ C).
For further information, ask your health care provider and read carefully the medication guide of this drug.
Diazepam 2mg for back pain
Table of Contents
Diazepam 2mg for back pain
Back pain symptoms:
Symptom of back pain may be simple muscle aching, shooting, burning, or stabbing sensation.
In some cases, pain may radiate down to the legs that lead to pain get worse by bending, twisting, standing, lifting, or walking.
Back pain makes you uncomfortable and debilitating.
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What are the causes of back pain?
There are many causes of back pain:
- Strain: strained muscles, muscle tension, fractures, injuries, or damaged disks.
Some activities may lead to strain like lifting something improperly or too heavy.
- Structural problems: eg osteoporosis, arthritis, ruptured disks, bulging disks, sciatica, or kidney problems.
- Sleep disorder.
- Cancer of spine.
- Infection of the spine.
- Nerve infection.
- Movement and posture:
- Pushing, pulling, or lifting.
- Muscle tension.
- Long driving sessions without break.
What is the risk factor of back pain?
A lot of risk factors are contributing to back pain:
- Older age.
- Poor physical fitness.
- Genetic factors.
- Medical issues like cancer or arthritis.
- Incorrect physical exercise.
- Stress, anxiety.
How to diagnose back pain?
Back pain can be diagnosed by imaging scans: x-rays, MRI, CT scans, bone scans, or Electromyography.
How to prevent suffering from back pain?
- Quit smoking.
- Weight loss.
- Avoid improper movement.
- Relieve stress.
- A healthy diet contains calcium and vitamin D.
When do you need to see a doctor?
You need to see your doctor if you:
- feels numbness or tingling.
- Your pain is not improved by rest.
- Back pain with fever.
- Unexplained weight loss.
- After fall and injury.
What is a treatment of back pain?
Treatment could be home remedies, medical treatment, physical therapy, or surgery.
- Home remedies: applying ice back or hot compressor and resting.
- Physical therapy.
- Surgical and other procedures.
- Alternative medicine: massage, yoga, acupuncture.
- Medications:
- Pain relivers: such as ibuprofen.
- Muscle relaxant: take care that muscle relaxant makes you dizzy and sleepy.
- Topical pain relievers.
What is diazepam?
Diazepam is one member of the benzodiazepine group.
Therapeutic indications of diazepam:
- Cerebral palsy.
- Muscle spasm.
- Adjunct therapy in seizure.
- Acute alcohol withdrawal.
- Premedication before surgery.
What are contraindications of diazepam?
Diazepam is contraindicated in the following cases:
- Hypersensitivity to benzodiazepine.
- Myasthenia gravis.
- Sleep apnea.
- Respiratory depression, acute and chronic respiratory insufficiency.
- Severe hepatic impairment.
- Pregnancy, or planning pregnancy.
Adverse effects of diazepam:
- Nervous system: drowsiness, ataxia, tremor, impaired motor ability, headache, and slurred speech.
- Cardiac disorders: rare side effects such as bradycardia.
- Vascular disorder: hypotension or syncope.
- Respiratory disorders: respiratory depression.
- General disorder: fatigue, palpitation, withdrawal symptoms, aggression, irritability, delirium, gastrointestinal disorder, sweating, and general malaise.
Precautions when you take diazepam:
- Do not drive or operate machinery.
- Do not take diazepam without checking your doctor.
- Do not use diazepam for a longer duration.
- Do not stop taking diazepam suddenly.
- Be careful if you are elderly, drinking alcohol, or taking another medication.
Overdose of diazepam:
The symptoms of diazepam overdose including ataxia, drowsiness, sedation, muscle weakness, bradycardia, nystagmus, in extreme overdosage may lead to coma, areflexia, cardio-respiratory depression, and apnea.
Management of diazepam overdose:
- Maintain a clear airway.
- Activated charcoal.
- Monitor level of consciousness.
- Management of hypotension by raising the foot.
- Benzodiazepine antagonist (flumazenil).
Diazepine 2mg for back pain:
- diazepam 2mg for back pain is one of the muscle relaxant medications use in the treatment of back pain, as providing effective pain relief for acute lower back pain.
- Although benzodiazepines are used in 300,000 US ED visits for LBP annually. The action of benzodiazepines may be related to centrally mediated action on the skeletal muscle or may instead work by mitigating anxiety about the condition or numbing a patient to the pain.
- Diazepam 2mg for back pain may be used alone as monotherapy or in combination with another analgesic medication such as NSAID (non-steroidal anti-inflammatory) e.g., naproxen.
- Benzodiazepine 2mg for back pain is more effective than NSAID monotherapy for the treatment of acute, non-traumatic low back pain.
Drug-drug interaction with diazepam 2mg for back pain:
They may be serious interaction if you take the following medication in concomitant use of diazepam:
- Mifepristone
- Sodium oxybate.
Other drugs need close monitoring during concomitant use with diazepam:
- Chloral hydrate.
Drug-Food interaction:
Food should be avoided during taking diazepam:
- Alcohol: you should not drink alcohol while taking diazepam.
This medication can increase the effects of alcohol. You may feel more drowsy, dizzy, or tired.
- Grapefruits: Grapefruit juice or grapefruit products may increase blood levels of diazepam.
Diazepam Online UK
Table of Contents
Diazepam Online UK
Diazepam Online UK is a drug that belongs to benzodiazepines. It is mainly used to treat conditions of anxiety disorders, seizures, alcohol withdrawal symptoms, benzodiazepine withdrawal symptoms, muscle spasms, and insomnia. It is also used as a premedication for inducing sedation or amnesia.
Benzodiazepines enhance the activity of certain neurotransmitters in the brain.
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Diazepam Online UK is found in the form of 2 mg, 5 mg, and 10 mg tablets:
The dose could be modified in case of:
- Hepatic impairment to 50% of maintenance dose.
- Renal Impairment the dose is only modified in case of prolonged usage.
The dose could also be modified in the case of pediatrics into:
- The drug is not recommended for < 6 months.
- 2-6 years: 0.5 mg/kg; which can be repeated in 4-12 hours.
- 6-12 years: 0.3 mg/Kg: which can be repeated in 4-12 hours.
- >12 years: 0.2 mg/Kg; which can be repeated in 4-12 hours.
What Diazepam tablets are used for?
In adults
- Diazepam is used to relieve short-term anxiety where the patient feels anxious with a fast heartbeat alone or with insomnia (trouble sleeping).
- Patients with Alcohol withdrawal symptoms.
- Patients suffering from cerebral palsy (a condition that affects the brain causing balance and movement problems).
In Children
- Help to treat muscle spasm caused by tetanus.
- Diazepam is prescribed for both adults and children to induce relaxation and sleepiness before an operation.
Diazepam Online UK is not contraindicated with any drug; however serious interactions could happen with lots of drugs:
Serious interactions (highly clinically significant, the risk of the interaction outweighs the benefit)
- Abametapir: Increase the effect of diazepam.
- Apalutamide: Decrease the effect of diazepam.
- Calcium/magnesium/potassium/sodium oxybates
- Metoclopramide intranasal.
- Erythromycin base
- Erythromycin Ethylsuccinate
- Erythromycin stearate.
- St John’s Wort.
Drugs need close monitoring (moderately clinically significant, use it only under special circumstances)
- Belladonna and opium.
- Buprenorphine subdermal implant.
- Buprenorphine long-acting injection.
- Chloral hydrate.
- Difenoxin HCl.
Minor interactions with (minimally clinically significant, minimize risk, and consider an alternative
Diazepam Online UK interacts with a total of 470 drugs in different ways such as:
- Xanax (alprazolam)
- Zyrtec (cetirizine)
- Lexapro (escitalopram)
- Noro (acetaminophen)
- Cymbalta (duloxetine)
- Fish oil (omega -3 polyunsaturated fatty acids)
- Vitamin C (ascorbic acid)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Diazepam Online UK should not be used if you are allergic to, or if you:
- Have Myasthenia gravis (a medical condition causing muscle weakness and tenderness)
- Have Narrow-angle glaucoma.
- Have Sleep apnea (breathing stop during sleep for short period)
- Have severe respiratory depression.
- Have renal diseases.
- Have hepatic diseases.
- Have a history of drug abuse or acute alcoholism.
Side Effects:
Like most drugs, Diazepam Online UK may cause one or more of the following side effects:
- Muscle weakness or spasm.
- Blurred vision.
- Urinary retention.
- Fast or irregular breathing.
- Lack of memory.
- Loss of appetite.
- Unusual changes in mood and behavior.
Consult your doctor immediately if you felt any of these signs.
Misuse of Diazepam Online UK may lead to symptoms of overdose such as:
- Loss of consciousness.
- Lack of coordination.
- Pale or blue lips.
- Loss of strength or energy.
- Double vision.
- Dry mouth.
- Decreased interest in sexual intercourse.
- Difficulty in swallowing.
Warnings:
- Diazepam has a risk for addiction, which can lead to overdose and death. Using this drug together with alcohol or other medications that may cause breathing problems (ex: codeine) may cause severe side effects including death.
- Diazepam Online UK is not to be stopped suddenly, the dose must be decreased gradually as prescribed by your doctor or you will suffer from severe withdrawal symptoms which includes life-threatening seizures.
- Diazepam Online UK is not considered a drug of choice in elderly patients as they may suffer cardiac arrest.
- Patients are advised not to drive or operate heavy machines while using diazepam.
Pregnancy and lactation:
- Pregnancy category: D
Use in life-threatening emergency cases only when no other safer drug is available. Positive evidence of human fetal risk.
Should be avoided in the first trimester of pregnancy due to the increased risk of congenital malformations.
Neonates exposed to high doses during labor should be monitored for irregularities in fetal heart rate and moderate respiratory depression.
Lactation:
Diazepam enters the breast milk so it is not recommended during lactation, so a decision should be taken to discontinue breastfeeding or discontinue the drug, taking into consideration the importance of the drug to the mother.
- Currently, Diazepam represents the first choice for the treatment of repetitive seizures as long as it is used according to the doctor’s instructions to reduce the fatal effect of overdose or addiction.
Herbal Viagra UK
Table of Contents
Herbal Viagra UK
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So, what is herbal Viagra UK?
But first, let’s talk about Impotence, erectile dysfunction, and decreased libido, and what do these terms mean?
Penile erection happens due to blood flowing in the penis, and then gets stored in small areas in the penis acting like sponges.
The process happens when messages are transferred from the brain to the nerves in the penis.
Impotence is the inability of the male to maintain an erection.
Erectile dysfunction is losing the erection faster than achieving orgasm.
Libido is the sexual desire or sexual drive which gets decreased due to several factors.
All of the above may cause marital problems causing relationship issues.
How to manage this group of dysfunctions?
First of all, a visit to the doctor is a must to make a complete physical examination, discuss other health problems, and if you are consuming any drugs that may be a reason for the condition.
Symptoms:
The main symptoms that may be persistent and require doctor intervention are,
- Problems in getting an erection
- Problems preserving an erection
- Decreased sexual desire
Causes:
Erectile dysfunction is a combined and complex process involving the brain, hormones, emotions, nerves, muscles, and blood vessels.
Sometimes, not just physical problems may cause this problem, but also, psychological ones may be a cause.
Physical causes
- Heart problems
- Atherosclerosis (blocked blood vessels)
- High levels of cholesterol
- Hypertension (high blood pressure)
- Diabetes
- Obesity
- Metabolic problems like those involving high blood pressure, high insulin levels, high cholesterol levels, and accumulation of body fats around the waist
- Parkinson’s disease (a problem in the brain causing shaking, stiffness, and coordination and balance problems)
- Multiple sclerosis (disease in the brain and spinal cord that may lead to disability)
- Peyronie’s disease (curved and painful erections caused by fibrous scar tissues inside the penis)
- Alcoholism
- Drug abuse
- Smoking
- Medications for prostate cancer and enlarged prostate
- Surgeries and injuries that may cause problems in the spinal cord or pelvic region
- Low testosterone levels
Medications may also cause erectile dysfunction, like
- Diuretics
- Antihypertensive drugs
- Antihistamines
- Antidepressants
- Parkinson disease drugs
- Antiarrhythmic drugs
- Tranquilizers
- Muscle relaxants
- NSAIDs (Non-steroidal anti-inflammatory drugs)
- Hormones
- Chemotherapy medications
- Prostate cancer drugs
- Anticonvulsant drugs
Abused drugs may also cause erectile dysfunction like
- Alcohol
- Amphetamines
- Barbiturates
- Cocaine
- Marijuana
- Methadone
- Nicotine
- Opiates
These drugs not only causing the erectile dysfunction by affecting the Central Nervous System but may also damage the blood vessels causing the condition to be permanent.
Viagra is a well-known drug used to treat this medical condition.
Its active ingredient is Sildenafil.
It works by making relaxation in the muscles found in the walls of blood vessels leading to an increase in the blood flow to particular areas of the body.
Dosage and administration:
Viagra is available as tablets with many concentrations, 25, 50, and 100 mg.
The usual dose is 50 mg before sexual activity by one hour.
It is taken only once per day.
According to the effectiveness of the drug, 25 mg and 100 mg can be used.
Patients with severe hepatic or renal impairment start with 25 mg.
Interactions:
Taking Viagra with other drugs may be extremely dangerous, here are lists of drugs that may cause problems when concomitantly used with Viagra.
Contraindicated drugs
- atazanavir
- cobicistat
- elvitegravir/cobicistat/emtricitabine/tenofovir DF
- isosorbide dinitrate
- isosorbide mononitrate
- nelfinavir
- nitroglycerin IV
- nitroglycerin PO
- nitroglycerin rectal
- nitroglycerin sublingual
- nitroglycerin topical
- nitroglycerin transdermal
- nitroglycerin translingual
- riociguat
- vericiguat
Serious, Use alternative
- abametapir
- alfuzosin
- amyl nitrite
- apalutamide
- asenapine
- chloramphenicol
- clarithromycin
- conivaptan
- crizotinib
- dabrafenib
- doxazosin
- eslicarbazepine acetate
- glyceryl trinitrate pr
- ivosidenib
- ketoconazole
- lonafarnib
- lopinavir
- mifepristone
- mitotane
- nafcillin
- ombitasvir/paritaprevir/ritonavir & dasabuvir
- oxcarbazepine
- pentobarbital
- phenobarbital
- phenoxybenzamine
- phentolamine
- phenytoin
- prazosin
- primidone
- ritonavir
- silodosin
- St John’s Wort
- terazosin
- tucatinib
- voxelotor
Always consult with your doctor about the combination of drugs you are taking.
So, how about herbal Viagra UK?
Panax ginseng, known as red ginseng, and so-called herbal Viagra UK.
It has an action on the cellular level to improve penis erection.
Seven studies have concluded suggestive evidence on the effectiveness of herbal Viagra UK for the treatment of erectile dysfunction.
Herbal Viagra UK is more effective in patients with high levels of lipids in their blood and patients with metabolic syndrome.
It is known to have anti-inflammatory actions, it improves lung functions and blood flow.
So, the most commonly asked question, Is herbal Viagra UK safe?
Herbal products don’t undergo the same standards as prescription and over-the-counter drugs do, so it is very hard to ensure their safety.
Viagra and similar products focus on the blood vessels in the penis, herbal products don’t specifically contain substances doing that.
Herbal Viagra UK may also cause dangerously low blood pressure especially those taking nitrate medications for their heart problems.
Additionally, the other ingredients in those products, not knowing them, nor their concentrations, and how they will affect the health of the patients.
Use neither drugs nor herbal products without the consultation of a doctor, this may be extremely dangerous on the patients.
Buy diazepam UK next day delivery
Table of Contents
Buy diazepam UK next day delivery
Diazepam is a benzodiazepine drug, the widely known family, which works on certain receptors called GABA (gamma amino-butyric acid) in the brain affecting the central nervous system (CNS), and are used for several medical conditions.
They attach to these receptors lowering the sensitivity of the brain to stimulation producing a calming effect.
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Benzodiazepines use:
- Alcohol withdrawal symptoms
- Anxiety
- Muscles spasms and stiffness
- Panic disorder
- Seizures
- Sleep disorders
- To induce sedation and amnesia before surgical operations
Diazepam is on this family, acts in the same way, and is used to treat several medical conditions from these conditions handled by benzodiazepines.
Diazepam has similar uses in adults and children.
Buy diazepam UK next-day delivery if you need it for any of the following cases.
Therapeutic indications of diazepam:
Adults
- Severe anxiety, disabling, and exposing the patient to irritating stress, which happens alone or is associated with insomnia, or with physical and psychiatric illness.
- Cerebral palsy (disorders causing problems with moving, maintaining balance, and posture).
- Muscle spasms and stiffness.
- Adjunctive therapy in certain types of epilepsy.
- Managing the acute symptoms happening with withdrawing alcohol.
- Premedication for the nervous patient before dental procedures.
- Inducing sedation in the ICU (intensive care unit) and before having surgery.
Children
- In some cases, diazepam is used to control tension and irritability in cerebral spasticity (where the muscles become stiff and the movements become jerky and stiff).
- Adjunctive therapy for the muscle spasm caused by a bacterial infection called tetanus.
Before you buy diazepam UK next day delivery, you have to tell your doctor if you have,
- allergy to diazepam, or other inactive ingredients in the pamphlet of the drug
- breathing problems, like shallow or slow breathing which may be severe
- depression accompanied by anxiety or not
- hyperactivity
- phobia (continuous fear from a specific place or situation) or from any other mental illness
- myasthenia gravis (easily weakened or tired muscles)
- sleep apnea (abnormal pauses in breathing during sleep for a short period)
- severe liver disease
- porphyria (a medical condition inherited from the parents causing skin blisters, abdominal pain, and central nervous system disorders)
You have also to inform your health care provider about the following before you buy diazepam UK next day delivery,
- history of alcohol or drug abuse
- heart and lung problems
- having psychological trauma like the death of a relative or a friend
- severe kidney failure
- low blood levels of albumin (a protein made by the liver)
- personality disorder
- arteriosclerosis (low blood flow to the brain)
- breathing difficulties
- depression
- suicidal thoughts or behaviors
- epilepsy
- smoking
Other considerations:
Before you buy diazepam UK next day delivery, consider the following,
- Mental side effects, like agitation, hyperactivity, restlessness, aggressiveness, nightmares, and hallucinations.
All of these side effects may occur with the use of diazepam especially with children and elders, contact your doctor immediately if you experience any of these symptoms.
- Amnesia, temporary memory loss which can happen with diazepam, it can be total or partial amnesia, especially with high doses, you have to contact your doctor at once if you experienced that.
- Dependence, if you feel that you need higher doses and longer duration, this is due to developing dependence on the drug, especially with those having a history of alcohol or drug abuse, you have also to contact your doctor and inform him about that.
- Tolerance, if the drug is not working as well as at the beginning of the treatment, talk to your doctor about that.
- Withdrawal, diazepam should be withdrawn gradually and not stopped suddenly, stopping the drug suddenly, withdrawal symptoms may occur.
Withdrawal symptoms:
- depression
- nervousness
- sleeping difficulties
- irritability
- sweating
- stomach cramps
- diarrhea
- worsening of the symptoms you are treated from is also a sign of withdrawing
- Withdrawal symptoms don’t stop at this point, other symptoms may also occur, mood changes, anxiety, restlessness, and changes in sleeping schedules, this may happen after taking the drug at low doses for a short period.
- If sudden stopping after taking high doses, confusion, hallucinations, shaking, and fast heartbeats may occur.
Driving and using machines:
Diazepam may cause sleepiness and poor coordination that can affect your ability to perform everyday activities, like driving, operating heavy machinery, and taking part in risky activities that can put you or others at risk.
You can only drive while taking diazepam if it is not affecting alertness.
Diazepam and lactose intolerance (a type of sugar):
If you are using diazepam tablets, be aware that they contain lactose, which may cause you problems if you suffer from lactose intolerance.
Buy diazepam UK next day delivery from trusted sources only, online websites may be trusted or non-trusted ones buy diazepam from pharma stores to make sure you are buying them from good places, but always take these drugs under the supervision of a doctor.
Paracetamol and Diazepam
Table of Contents
Paracetamol and Diazepam
Two drugs are taken together and there is no problem with it?
Two drugs, one for anxiety and the other one for pain, two that are solving your most irritating drugs, and with no interactions happening.
Yes, these two drugs are Paracetamol and Diazepam.
So, what are Paracetamol and Diazepam?
Let’s go to know them together.
Paracetamol, known in the United States as acetaminophen, the most commonly known drug for pain and fever.
It is known as the safest drug to use, it is safe to be used in pregnant women, breastfeeding, and even in neonates.
Paracetamol is used in many conditions, like headache, muscle aches, arthritis (Swelled and tendered joints, distinctive by pain and stiffness of joints), backache, toothaches, colds, and fevers.
It relieves pain but doesn’t affect the inflammation and swelling of joints.
Warnings:
The maximum dose taken from Paracetamol is 1 gram per dose and 4 grams per day.
Taking care of the dose and knowing the maximum dose is very important to avoid overdosing.
Overdose can cause serious harm, like damaging the liver.
If you drink more than 3 alcoholic drinks per day, or if you are suffering from alcoholic liver disease (liver cirrhosis), you should not use Paracetamol without a consult with your doctor.
If the doctor decided you can take Paracetamol when you are drinking more than 3 alcoholic drinks per day, the maximum dose approved is 2 grams per day.
Using over-the-counter cold, cough, allergy, and pain medications may cause overdose, as most of these drugs contain Paracetamol.
Read the medication guide to make they don’t contain Paracetamol in them.
Interactions:
There are no completely contraindicated drugs to be used with Paracetamol, but there is a list of drugs that cause serious interaction, and an alternative drug should be used.
- lonafarnib
- pexidartinib
- pretomanid
There is another list of drugs that when concomitantly used with Paracetamol, close monitoring is needed.
- apalutamide
- avapritinib
- axitinib
- bupivacaine implant
- busulfan
- dapsone topical
- eltrombopag
- exenatide injectable solution
- exenatide injectable suspension
- flibanserin
- imatinib
- isoniazid
- ivacaftor
- lemborexant
- levonorgestrel oral/ethinylestradiol/ferrous bisglycinate
- lixisenatide
- lomitapide
- midazolam intranasal
- mipomersen
- tazemetostat
- tetracaine
- tinidazole
- warfarin
These are not the only drugs interacting with Paracetamol, always consult with your doctors about the drugs you are taking before taking a new one.
Side effects:
- Angioedema (swelling below the skin, it may be due to an allergy to a trigger or a medicine)
- Disorientation
- Dizziness
- Pruritic maculopapular rash (blisters on a flat and red patch of skin)
- Rash
- Hyperammonemia (Excess ammonia in the blood leading to brain injury and death)
- Stevens-Johnson syndrome (a rare and dangerous disorder of the skin and mucous membrane)
- Urticaria
- Gastrointestinal hemorrhage
- Toxic epidermal necrolysis (a rare and serious skin condition)
- Laryngeal edema (Complication happens as a result of intubation)
- Agranulocytosis (very dangerous blood disorder)
- Leukopenia (low count of white blood cells)
- Neutropenia (lower number of neutrophils than normal, a type of white blood cells)
- Hepatotoxicity
- Liver failure
- Nephrotoxicity (a kidney problem)
- Pneumonitis (inflammation of lung tissues)
What about Diazepam?
Diazepam is a benzodiazepine, used in conditions like anxiety, alcohol withdrawal symptoms, seizures, and muscle spasms.
It is also used in providing sedation before having surgery, a dental procedure, or if sedation is required in the ICU (Intensive care unit).
Diazepam works by affecting certain neurotransmitters calming the brain and nerves.
Warnings:
Opioid medications like hydrocodone, oxymorphone, morphine, codeine, and fentanyl, can cause a serious case of shallow breathing or even stop breathing if used with diazepam.
Diazepam may cause misuse, if you have a history of abuse or addiction to any kind of drugs or alcohol, you have to tell your doctor before taking it.
Diazepam may cause a serious allergic reaction, take care of any signs of hives, swelling of face, lips, and tongue, and rash.
This drug did not prove effectiveness and safety in children younger than 6 months old, so it should not I children younger than 6 months old.
Interactions:
Like Paracetamol, diazepam doesn’t have completely contraindicated with it but has drugs causing serious interactions, and an alternative drug should be used.
- abametapir
- apalutamide
- benzhydrocodone/acetaminophen
- calcium/magnesium/potassium/sodium oxybates
- carbamazepine
- cimetidine
- clarithromycin
- darunavir
- erythromycin base
- erythromycin ethylsuccinate
- erythromycin lactobionate
- erythromycin stearate
- fedratinib
- hydrocodone
- idelalisib
- ivosidenib
- ketoconazole
- lonafarnib
- metoclopramide intranasal
- mifepristone
- nefazodone
- rifabutin
- rifampin
- selinexor
- sodium oxybate
- St John’s Wort
- sufentanil SL
- tipranavir
- tucatinib
- valerian
- voxelotor
Another list of drugs needs close monitoring when used with diazepam, always tell your doctor about drugs you are taking before taking a new one.
Side effects:
There are common and less common side effects, in this article, we will only talk about the common ones.
- Ataxia (a group of disorders affecting balance, coordination, and speech)
- Euphoria
- Incoordination
- Sleeplessness
- Rash
- Diarrhea
Finally, Paracetamol and diazepam have no problem with being used together, there are no interactions between them but always consult with your doctor about the doses and times of taking drugs to accomplish the effectiveness and safety from this interaction.
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Amitriptyline and Diazepam
Table of Contents
Amitriptyline and Diazepam
When different drugs are used together, different interactions may occur, like using amitriptyline and diazepam are used together, what is the kind of interaction between them?
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If they have similar actions, additive effects may happen.
If they have opposite actions, canceling effects may happen.
These interactions may cause an increase or decrease in the effectiveness of the drugs or even the side effects.
This happens due to increase or decrease in:
- The absorption of the drug
Like drugs not taken with food as food may affect their absorption as an example, fibers like wheat bran slows down the absorption of digoxin and decreases its effectiveness.
- The distribution of the drug
Like drugs causing others to be freer, not binding to plasma proteins, making their concentration higher, which may cause toxicity, for example, diazepam and phenytoin, diazepam makes phenytoin more available, which increases the risk for toxicity.
- The metabolism of the drug (the alteration of the drug to be excreted outside the body)
Some drugs interact by inducing or inhibiting the enzymes responsible for metabolizing other drugs, which result in an increase or decrease in the concentration of these drugs, for example, Phenytoin and Rifampicin, are enzyme inducers, resulting in the decrease of the interacted drug as they enhance the excretion of it from the body.
- The elimination of the drug
Patients with renal impairment taking drugs excreted through the urine must get altered doses to avoid the accumulation of the drugs in the body leading to toxic doses.
So, what is amitriptyline, and what is diazepam, and what is the kind of interaction between amitriptyline and diazepam?
Amitriptyline belongs to a family of drugs called tricyclic antidepressants.
It is used in mental and mood problems, like depression.
Amitriptyline helps in relieving anxiety and tension, improving mood, sleeping better, and increasing your level of energy.
It works by affecting certain neurotransmitters in the brain like serotonin.
Amitriptyline is also used in certain eating disorders and migraine headaches.
There are also off-label uses of amitriptyline:
- Increase in the production of saliva
- Sleeping problems
- Irritable bowel syndrome (gastrointestinal disorder causing chronic discomfort)
- Neuralgia caused after the infection of herpes zoster
Neuralgia is caused by damaged or diseased nerves, leading to burning, stabbing pains, or aches.
- Chronic pain
- Interstitial cystitis (bladder problem causing pain and pressure in the pelvis, bladder, also causing urinary frequency or urgency)
- Migraine (severe and recurrent headache)
- Anxiety
- Post-traumatic stress disorder (disorder happening after a traumatic event like feeling extreme fear, shock, or helplessness)
Dosage and administration:
Amitriptyline is found in tablet form with many concentrations.
Depression
25 – 50 mg initially, increased by 25 mg every 5 – 7 days, till reaching 100 – 200 mg per day.
The dose may be divided through the day or just taken at bedtime.
If needed, the dose may be increased to 300 mg per day.
Neuralgia caused after the infection with herpes zoster
65 – 100 mg per day, and it is used for at least 3 weeks.
Migraine
10 – 25 mg per day.
The dose may range from 10 to 400 mg per day.
Eating disorder
150 mg per day for 8 weeks.
Contraindicated drugs:
Drugs that should never be used with amitriptyline.
- disopyramide
- dronedarone
- ibutilide
- indapamide
- iobenguane I 123
- isocarboxazid
- pentamidine
- phenelzine
- pimozide
- procainamide
- procarbazine
- quinidine
- safinamide
- selegiline
- sotalol
- tranylcypromine
What about Diazepam?
Diazepam is one of a very famous family called benzodiazepines.
It is used in treating anxiety, alcohol withdrawal symptoms, seizures, providing sedation in the ICU (intensive care unit), providing sedation before having surgery, relaxation of spastic muscles, and in status epilepticus.
Dosage and administration:
Diazepam is available in many dosage forms, tablets, oral solutions, rectal gels, injectable solutions, and intramuscular devices, with many different concentrations.
Anxiety
2 – 10 mg every 6 – 12 hours.
Maximum dose: 30 mg every 8 hours
Alcohol withdrawal symptoms
10 mg every 6 – 12 hours during the first 24 hours.
The dose is reduced to 5 mg every 6 – 8 hours.
Muscle spasms
2 – 10 mg every 6 – 8 hours.
There are no completely contraindicated drugs with diazepam, but drugs are causing serious interactions, and you have to use an alternative drug.
Serious interactions causing drugs:
- abametapir
- apalutamide
- benzhydrocodone/acetaminophen
- calcium/magnesium/potassium/sodium oxybates
- carbamazepine
- cimetidine
- clarithromycin
- darunavir
- erythromycin base
- erythromycin ethylsuccinate
- erythromycin lactobionate
- erythromycin stearate
- fedratinib
- hydrocodone
- idelalisib
- ivosidenib
- ketoconazole
- lonafarnib
- metoclopramide intranasal
- mifepristone
- nefazodone
- rifabutin
- rifampin
- selinexor
- sodium oxybate
- St John’s Wort
- sufentanil SL
- tipranavir
- tucatinib
- valerian
- voxelotor
Amitriptyline and diazepam together may cause increased side effects, like dizziness, drowsiness, confusion, and concentration difficulties.
Elder patients especially experience thinking and judgment impairment, and problems with coordination.
Alcohol is really dangerous if used with amitriptyline and diazepam.
Driving and operating heavy machinery should not be performed unless making sure about how the drug will affect the patient.
Always confirm with your doctor the information mentioned in a medical article.
Cheap Valium Uk
Table of Contents
Cheap Valium Uk
Pharmastores.com is one of the best online drug stores to get a cheap valium UK.
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The active constituent of Valium is diazepam which belongs to the benzodiazepine group, it is used for treating anxiety, spasticity, epilepsy and as anxiolytic before operations.
The recommended dose of diazepam:
In adults
- Anxiety or mental health problems: start with 5mg to a maximum dose of 30mg each day, in divided doses.
- To help you sleep: 5mg-15mg at bedtime.
- With cerebral palsy or other spasticities: the dose may range from 5mg to 60mg each day, in divided doses.
- To control muscle spasms: start with a dose of 5mg to reach 15mg each day, in divided doses.
- To help epilepsy: start with a dose of 2mg to a maximum of 60mg each day, in divided doses.
- To help with alcohol withdrawal symptoms: 5mg to 20mg, which may be repeated after 2 to 4 hours if necessary.
- Before dental treatment: you can take valium tablets 5mg the night before treatment and 5mg on waking and 5mg two hours before the appointment.
- Before an operation: 5mg-20mg
Use in children
For tension and irritability associated with cerebral spasticity: 5mg to 40mg each day, in divided doses.
As an anxiolytic before an operation by a dose of 2mg-10mg.
Elderly or Frail
The effect of valium may be exaggerated If you are elderly or frail such as confusion, and your doctor will prescribe lower doses to you. The dose in these situations cannot exceed half the adult dose.
Kidney or liver impairment
Valium tablets may accumulate in your body in case of liver or kidney problems. you may need a lower dose.
How to take valium tablets?
Always follow the instructions of your doctor about Valium, do not change the dose by yourself. Make sure that you take this medicine exactly as your doctor or pharmacist has told you.
Always remember that cheap Valium uk tablets are available at pharmastores.net. know that Valium tablets cannot be taken for longer than 4 weeks. Do not crush Valium tablets, Swallow them whole, with a glass of water.
Valium overdose
if you take more valium tablets than you should or If you (or someone else) swallow a lot of valium tablets at the same time, or you think a child may have swallowed any, tell your doctor immediately.
Signs of an overdose
- Clumsiness and loss of coordination
- Feeling sleepy or deep sleep
- Speech problems
- Irregular or slow heartbeat
- Uncontrolled eye movement
- Muscle weakness or excitement
- Coma in case of extreme overdose (unrousable unconsciousness), breathing difficulties and reflex problems.
Missed doses
Do not take double the dose of valium tablets to make up for a forgotten dose.
Examples of drugs that can interact with valium:
- Isoniazid (antiuburcolosis drug)
- Oral contraceptives, breakthrough bleeding can occur if you take valium with oral contraceptives.
- Cisapride can decrease the effect of diazepam by accelerating its elimination from the body.
- Levodopa (used to treat Parkinson’s disease).
- Valproic acid (antiepileptic drug).
- ketamine (an anaesthetic).
- Nabilone (to treat nausea and vomiting).
- Alpha-blockers, beta-blockers (antihypertensive drugs).
Valium and opioids
Concomitant use of valium tablets and opioids (strong painkillers) increases the risk of difficulties in breathing (respiratory depression), drowsiness, coma and may be life-threatening, so use them together if the other options are not available.
Your doctor will limit the duration and doses in case of concomitant use.
Do not forget to tell your doctor about all the medicines you take as some types of these opioids can be a part of cough suppressants OTC preparation.
Valium UK tablets with food and drink
Avoid drinking alcohol while taking diazepam as alcohol increases the sedative effect of diazepam and makes you drowsy. Some food can also increase the concentration of diazepam in your blood like grapefruit juice. If you are older than 65 years or suffer from liver disease, this could possibly increase the sedative effects of valium tablets and you should speak to your doctor or pharmacist. Drinks containing caffeine may reduce the effects of valium.
Pregnancy, breast-feeding and fertility
Do not take valium UK tablets if you are pregnant, or planning to be pregnant or breastfeeding. If you take valium near the end of your pregnancy (or during labour) this may harm your baby like low temperature, be restless, difficulty in feeding, have breathing problems.
Driving and using machines
Valium tablets can affect daily normal activities as they may make you sleepy, forgetful, have poor coordination, so you should not operate machinery, or drive, or take part in any activities that require a high level of concentration.
Stopping valium tablets and Withdrawal Effects
You should not stop valium tablets suddenly your doctor will taper the dose according to your tolerance and response.
Withdrawal symptoms can occur If you stop taking valium tablets suddenly such as:
- depression
- nervousness
- difficulty in sleeping
- irritability
- sweating
- upset stomach/diarrhoea
You may also experience anxiety, mood changes, restlessness and changes in sleep patterns. These effects may occur even with a short duration of use and small doses.
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